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重视酒精性肝炎的临床研究
Importance of the clinical research on alcoholic hepatitis
文章发布日期:2019年02月03日  来源:  作者:王炳元  点击次数:199次  下载次数:113次

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【摘要】:酒精性肝炎(AH)是肝脏的一种无菌性炎症性损伤,大多发生在慢性肝病(脂肪肝、肝硬化)的基础上,因短期内大量饮酒所致肝病的急性恶化,是酒精性肝病严重的表现形式。AH的预后取决于治疗的时机和方法,肝功能可迅速恢复,也可迅速恶化至多脏器功能衰竭。不少临床医生还缺乏对AH的早期识别和及时处理的经验,主要原因是AH缺乏典型的临床表现,又缺少特异性的辅助检查,从而影响临床诊断,贻误治疗时机。因此,重视AH的临床研究,总结出临床真实世界的大数据,制订相应的专家共识已经势在必行。
【Abstract】:Alcoholic hepatitis (AH) is a non-infectious inflammatory injury of the liver and often occurs on the basis of chronic liver disease including fatty liver disease and liver cirrhosis. Acute exacerbation of liver disease due to heavy drinking within a short period of time is a severe manifestation of AH. The prognosis of AH depends on treatment timing and methods, and liver function can quickly recover or rapidly deteriorate into multiple organ failure. Many clinicians lack the experience in early identification and timely treatment of AH, due to a lack of typical clinical manifestations and specific auxiliary examinations, which affects clinical treatment, delays treatment, and exposes some AH patients to the risk of death. Therefore, it is imperative to conduct more clinical studies on AH, summarize real-world data, and develop expert consensus.
【关键字】:肝炎, 酒精性; 诊断; 述评
【Key words】:hepatitis, alcoholic; diagnosis; editorial
【引证本文】:WANG BY. Importance of the clinical research on alcoholic hepatitis[J]. J Clin Hepatol, 2019, 35(3): 469-471. (in Chinese)
王炳元. 重视酒精性肝炎的临床研究[J]. 临床肝胆病杂志, 2019, 35(3): 469-471.

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