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肝(窦)前型非肝硬化门静脉高压症的诊断与治疗及其面临的困境
Diagnosis and treatment of pre-hepatic (sinusoidal) non-cirrhotic portal hypertension and related difficulties
文章发布日期:2018年12月17日  来源:  作者:徐航飞,丁惠国  点击次数:344次  下载次数:126次

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【摘要】:肝(窦)前型非肝硬化性门静脉高压症(NCPH)是一组以门静脉高压症为突出表现的血管异质性疾病,病因复杂。与肝硬化门静脉高压症相比,NCPH患者肝功能基本正常,肝静脉压力梯度正常或轻度增加,预后较好,极易误诊为不明原因肝硬化门静脉高压症,肝脏病理是诊断“金标准”。目前,非选择性β受体阻滞剂及内镜是NCPH的主要治疗方法,但是缺乏前瞻性多中心、大样本、高质量的临床证据。
【Abstract】:Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension is a group of vascular heterogeneous diseases with portal hypertension as the prominent manifestation and has a complex etiology. Compared with the patients with cirrhotic portal hypertension, the patients with pre-hepatic (sinusoidal) non-cirrhotic portal hypertension have normal liver functions, normal or a mild increase in hepatic venous pressure gradient, and better prognosis. Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension may easily be misdiagnosed as unexplained cirrhotic portal hypertension, and liver pathology is the gold standard for diagnosis. Non-selective β-receptor blockers and endoscopy are major therapies for this disease, but there is a lack of high-quality clinical evidence from large-scale prospective multicenter studies.
【关键字】:高血压, 门静脉; 诊断; 治疗
【Key words】:hypertension, portal; diagnosis; therapy
【引证本文】:XU HF, DING HG. Diagnosis and treatment of pre-hepatic (sinusoidal) non-cirrhotic portal hypertension and related difficulties[J]. J Clin Hepatol, 2019, 35(1): 13-17. (in Chinese)
徐航飞,丁惠国. 肝(窦)前型非肝硬化门静脉高压症的诊断与治疗及其面临的困境[J]. 临床肝胆病杂志, 2019, 35(1): 13-17.

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