首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2018年 11期 肝脏病理 => 综述 =>肝癌局部消融治疗引起的热休克蛋白..
肝癌局部消融治疗引起的热休克蛋白70增强免疫研究进展
Research advances in immune enhancement by heat shock protein 70 induced by local ablation for liver cancer
文章发布日期:2018年09月30日  来源:  作者:塔来提·吐尔干, 吐尔干艾力·阿吉  点击次数:245次  下载次数:20次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:肝癌仍严重威胁人类健康,探索治疗肝癌的新型微创方法迫在眉睫。系统回顾了肝癌在我国的一般情况,叙述了肝癌目前的局部消融及免疫治疗方法。介绍了纳秒脉冲治疗肝癌的基本原理和热休克蛋白70在抗肿瘤免疫中的作用机制。提出纳秒脉冲作为一种外源性电刺激会使机体中的热休克蛋白7表达升高,来加强机体的抗肿瘤免疫。完善了纳秒脉冲治疗肝癌的免疫学机制,并为肝癌的免疫治疗提供了新思路。
【Abstract】:Liver cancer still threatens human health nowadays, so it is urgent to explore new minimally invasive methods for the treatment of liver cancer. This article reviews the general status of liver cancer in China and describes local ablation and immunotherapy for liver cancer. This article also introduces the basic principle of nanosecond pulse in the treatment of liver cancer and the mechanism of action of heat shock protein 70 (HSP70) in antitumor immunity and points out that as an exogenous electrical stimulation, nanosecond pulse can increase the expression of HSP70 in the body to strengthen the body′s anti-tumor immunity. This article perfects the immunological mechanism of nanosecond pulse in the treatment of liver cancer and provides new thoughts for immunotherapy for liver cancer.
【关键字】:肝肿瘤; HSP70热休克蛋白质类; 导管消融术; 综述
【Key words】:liver neoplasms; HSP70 heat-shock proteins; catheter ablation; review
【引证本文】:TALAITI TEG, TUERGANAILI AJ. Research advances in immune enhancement by heat shock protein 70 induced by local ablation for liver cancer[J]. J Clin Hepatol, 2018, 34(11): 2438-2442. (in Chinese) 塔来提·吐尔干, 吐尔干艾力·阿吉. 肝癌局部消融治疗引起的热休克蛋白70增强免疫研究进展[J]. 临床肝胆病杂志, 2018, 34(11): 2438-2442.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号