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上海地区乙型肝炎患者焦虑和抑郁状况及相关因素调查
Current status of anxiety and depression among hepatitis B patients in Shanghai, China and related influencing factors
文章发布日期:2018年08月07日  来源:  作者:马希权, 熊伍军, 刘璐,等  点击次数:393次  下载次数:64次

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【摘要】:目的探索上海地区乙型肝炎患者中焦虑和抑郁的发病情况以及相关影响因素。方法采用横断面调查,选取2016年6月-2016年12月就诊于上海三家医院(同济大学附属东方医院、公共卫生临床中心、浦东新区南华医院)的乙型肝炎患者917例。评估采用医院焦虑与抑郁量表(HADS)及自编社会人口学问卷对患者实测。计量资料两组间比较采用独立样本t检验,多组间比较采用单因素方差分析,进一步两两比较采用LSD-t检验。采用多元线性回归分析焦虑和抑郁得分与患者人口学、社会经济学因素之间的关系。结果由HADS评估的焦虑和抑郁症状的发生率分别为87.6%和90.7%。乙型肝炎患者焦虑的严重程度与患者的年龄、家庭收入水平和受教育程度有关(F值分别为3.518、6.416、3.322,P值均<0.05);抑郁的严重程度与患者的年龄、婚姻状况、家庭收入水平、职业和并发症有关(F=2.904、t=2.242、F=22.840、F=9.235、F=11.870、t=2.246,P值均<0.05)。更高教育程度、更高收入水平和单身状态是抑郁发生的危险因素(P值均<0.05);更高收入水平和年纪增长与患者的焦虑明显相关(P值均<005)。结论目前上海地区乙型肝炎患者的精神状况不容乐观,其焦虑和抑郁症状的发生率较高,这一结果也提醒医务工作者更应该关注乙型肝炎患者的心理健康问题。
【Abstract】:ObjectiveTo investigate the prevalence of anxiety and depression among hepatitis B patients in Shanghai, China and related influencing factors. MethodsA cross-sectional survey was performed among 917 hepatitis B patients who were treated in Shanghai East Hospital, Tongji University, Shanghai Public Health Clinical Center, and Nanhua Hospital in Pudong New Area from June to December, 2016. The Hospital Anxiety and Depression Scale (HADS) and a self-designed social demography questionnaire were used for evaluation. The independent samples t-test and a one-way analysis of variance were used for comparison of continuous data between groups, and a multivariate linear regression analysis was used to analyze the correlation of anxiety and depression scores with demographic and socioeconomic factors. ResultsThe prevalence rates of anxiety and depression symptoms assessed by HADS were 87.6% and 90.7%, respectively. The severity of anxiety in hepatitis B patients was associated with age, family income, and educational level (F=3.518, 6.416, and 3.322, all P<0.05), and the severity of depression was associated with age, marital status, family income, occupation, and complications (F=2.904, t=2.242, F=22.840, F=9.235, F=11.870, t=2.246, all P<0.05). High educational level, high income, and single status were risk factors for depression(all P<0.05), and high income and the increase in age were significantly associated with anxiety(all P<0.05). ConclusionAt present, the mental state of hepatitis B patients in Shanghai is not optimistic, with high prevalence rates of anxiety and depression. The results remind medical workers that they should pay attention to the mental health of hepatitis B patients.
【关键字】:肝炎, 乙型; 焦虑; 抑郁; 横断面研究
【Key words】:hepatitis B; anxiety; depression; cross-sectional studies
【引证本文】:MA XQ, XIONG WJ, LIU L, et al. Current status of anxiety and depression among hepatitis B patients in Shanghai, China and related influencing factors[J]. J Clin Hepatol, 2018, 34(8): 1664-1668. (in Chinese)
马希权, 熊伍军, 刘璐, 等. 上海地区乙型肝炎患者焦虑和抑郁状况及相关因素调查[J]. 临床肝胆病杂志, 2018, 34(8): 1664-1668.

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