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妊娠期肝衰竭的病因研究进展
Research advances in the etiology of liver failure during pregnancy
文章发布日期:2018年08月06日  来源:  作者:张宝忠,周鹏志  点击次数:269次  下载次数:14次

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【摘要】:妊娠期肝衰竭是发生于妊娠期间的﹑由各种致病因素引起的严重肝损伤,是威胁孕产妇及胎儿生命的危重症之一。将妊娠期肝衰竭的病因归纳为病毒性因素、非病毒性因素、妊娠特发因素以及不明原因四大类,叙述了不同病因导致的妊娠期肝衰竭的发病率、病死率及地域分布特点等方面的研究进展,同时比较了不同病因之间临床特点的差异性。认为对不同病因导致的妊娠期肝衰竭,治疗方案及预后可截然不同,病因诊断对于该疾病的治疗具有重要的指导性意义,临床上对怀疑该病的重症孕产妇应及时进一步的检查以明确病因,并及早给予相应的治疗。
【Abstract】:Liver failure during pregnancy is a serious liver injury caused by various pathogenic factors during pregnancy and is a critical disease that threatens the life of the mother and the fetus. The causes of liver failure during pregnancy are classified into viral factors, non-viral factors, pregnancy-specific factors, and unknown causes. This article describes the research advances in the incidence rates, deaths, and geographical distribution characteristics of liver failure during pregnancy of different etiologies and compares the clinical features of liver failure during pregnancy of different etiologies. It is pointed out that liver failure during pregnancy of different etiologies has entirely different treatment regimens and prognoses, and the etiological diagnosis has important guiding significance in the treatment of this disease. Further examination should be performed for critically ill pregnant women suspected of this disease to determine the etiology, and appropriate treatment should be given as early as possible.
【关键字】:肝功能衰竭; 妊娠并发症; 病因; 综述
【Key words】:liver failure; pregnancy complications; etiology; review
【引证本文】:ZHANG BZ, ZHOU PZ. Research advances in the etiology of liver failure during pregnancy[J]. J Clin Hepatol, 2018, 34(9): 2012-2016. (in Chinese)
张宝忠, 周鹏志. 妊娠期肝衰竭的病因研究进展[J]. 临床肝胆病杂志, 2018, 34(9): 2012-2016.

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