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门静脉高压无创评估方法的研究进展
Research advances in noninvasive assessment of portal hypertension
文章发布日期:2018年07月06日  来源:  作者:周昊,杨建江,汤善宏,等  点击次数:344次  下载次数:73次

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【摘要】: 摘要:肝硬化失代偿期患者存在不同程度门静脉高压,当门静脉压力达到一定程度,将出现各种严重的临床并发症,威胁患者生命,因此门静脉压力的评估对此类患者的临床管理及预后至关重要。由于门静脉独特的解剖学特点,直接测量门静脉压力比较困难,目前国内外普遍用肝静脉压力梯度值来替代门静脉压力值,但肝静脉压力梯度测定属于介入方法,也难以在临床常规开展。因此,门静脉高压无创评估成为目前研究热点。本文旨在对血清标志物、超声弹性成像、CT、MRI/磁共振弹性成像在门静脉高压无创评估中的研究进展作一综述。
【Abstract】:Patients with decompensated cirrhosis often have varying degrees of portal hypertension, and when portal pressure reaches a certain threshold, various clinical complications may occur and even threaten patients′ lives. Therefore, portal pressure assessment is important for the clinical management and prognosis of such patients. Due to the anatomical characteristics of the portal vein, it is difficult to measure portal pressure directly. At present, hepatic venous pressure gradient is used to replace portal pressure in China and foreign countries. However, the measurement of hepatic venous pressure gradient is an interventional procedure and is difficult to perform in clinical practice. Therefore, noninvasive assessment of portal hypertension has become a research hotspot. This article reviews the research advances in the roles of serum markers, ultrasound elastography, computed tomography, and magnetic resonance imaging/magnetic resonance elastography in noninvasive assessment of portal hypertension.
【关键字】:肝硬化; 高血压, 门静脉; 诊断; 综述
【Key words】:liver cirrhosis; hypertension, portal; diagnosis; review
【引证本文】:ZHOU H, YANG JJ, TANG SH, et al. Research advances in noninvasive assessment of portal hypertension[J]. J Clin Hepatol, 2018, 34(8): 1783-1787. (in Chinese)
周昊, 杨建江, 汤善宏, 等. 门静脉高压无创评估方法的研究进展[J]. 临床肝胆病杂志, 2018, 34(8): 1783-1787.

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