首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 8期 自身免疫性胰腺炎 => 胰腺疾病 =>胆囊结石并发急性胆源性胰腺炎..
胆囊结石并发急性胆源性胰腺炎的危险因素分析
Risk factors for gallstones complicated by acute biliary pancreatitis
文章发布日期:2018年07月06日  来源:  作者:王宪鹏,孟宪志  点击次数:300次  下载次数:50次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:目的探讨胆囊结石并发急性胆源性胰腺炎(ABP)的高危因素。方法收集2014年1月-2017年9月因腹痛收入哈尔滨医科大学附属第一医院普外科并确诊为胆囊结石患者的临床资料。计数资料2组间比较采用χ2 检验。多因素分析采用二分类logistic回归分析法。结果共收集700例胆囊结石患者,其中167例并发ABP,发生率23.86%。单因素分析显示,性别、胆囊大小、胆囊壁厚度、胆囊结石大小、胆囊结石多少、有无胆总管结石与是否并发ABP有关(P值均<0.05)。将单因素分析具有统计学差异的因素进行多因素logistic回归分析显示男性[比值比(OR)=1.879, 95%可信区间(95%CI):1.279~2.758]、胆囊大小异常(OR=0.282,95%CI:0.184~0.434)、胆囊壁厚度≤3 mm(OR=2.245,95%CI:1.490~3.383)、胆囊结石直径>1 cm(OR=0.438,95%CI:0.249~0.769)、胆囊单发结石(OR=0.222,95%CI:0.130~0.378)、合并胆总管(OR=2.775,95%CI:1.694~4.546)与ABP发生显著相关(P值均<0.05)。结论男性、胆囊大小正常、胆囊壁厚≤3 mm、胆囊结石直径≤1 cm、胆囊多发结石、合并胆总管结石均为胆囊结石患者并发ABP的独立危险因素。
【Abstract】:ObjectiveTo investigate the risk factors for gallstones complicated by acute biliary pancreatitis (ABP). MethodsA retrospective analysis was performed for the clinical data of patients who were admitted to Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, from January 2014 to September 2017 due to abdominal pain and then diagnosed with gallstones. The chi-square test was used for comparison of categorical data between groups, and the binary logistic regression analysis was used as multivariate analysis. ResultsA total of 700 patients with gallstones were enrolled, among whom 167 were complicated by ABP, resulting in an incidence rate of 23.86%. The univariate analysis showed that sex, gallbladder size, gallbladder wall thickness, gallstone size, the number of gallstones, and presence or absence of common bile duct stones were associated with the development of ABP (all P<0.05). A multivariate analysis was performed for the factors with statistical difference identified by the univariate analysis, and the results showed that male sex (odds ratio [OR]=1.879, 95% confidence interval [CI]: 1.279-2.758, P<0.05), abnormal gallbladder size (OR=0.282, 95%CI: 0.184-0.434, P<0.05), gallbladder wall thickness ≤3 mm (OR=2.245, 95%CI: 1.490-3.383, P<0.05), gallbladder stone diameter >1 cm (OR=0.438, 95%CI: 0.249-0.769, P<0.05), single gallstone (OR=0.222, 95% CI: 0.130-0.378, P<0.05), and presence of common bile duct stones (OR=2.775, 95%CI: 1.694-4.546, P<0.05) were significantly associated with the development of ABP. ConclusionMale sex, normal gallbladder size, gallbladder wall thickness ≤3 mm, gallbladder stone diameter ≤1 cm, multiple gallstones, and presence of common bile duct stones are independent risk factors for ABP in patients with gallstones.
【关键字】:胆囊结石病; 胰腺炎; 危险因素
【Key words】:cholecystolithiasis; pancreatitis; risk factors
【引证本文】:WANG XP, MENG XZ. Risk factors for gallstones complicated by acute biliary pancreatitis[J]. J Clin Hepatol, 2018, 34(8): 1728-1732. (in Chinese)
王宪鹏, 孟宪志. 胆囊结石并发急性胆源性胰腺炎的危险因素分析 [J]. 临床肝胆病杂志, 2018, 34(8): 1728-1732.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号