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肝细胞癌分子靶向治疗进展
Advances in molecular targeted therapy for hepatocellular carcinoma
文章发布日期:2018年06月07日  来源:  作者:陈万勇,任宁  点击次数:815次  下载次数:169次

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【摘要】:目前肝细胞癌(HCC)的主要治疗手段包括手术、化疗和放疗等。随着分子生物学技术的不断发展,分子靶向治疗迅速崛起。针对HCC发生发展相关的信号通路中某些特定位点设计靶向药物,成为HCC治疗研究的新热点。就近年来HCC的相关信号通路和对应的靶向治疗药物进行简要阐述。
【Abstract】:At present, the main treatment methods for hepatocellular carcinoma(HCC) include surgery, chemotherapy, and radiotherapy. With the development of molecular biological techniques, the field of molecular targeted therapy is developing rapidly. The design of targeted drugs based on some specific sites in the signaling pathways involved in the development and progression of HCC has become a new research hotspot. This article elaborates on the pathways involved in the development and progression of HCC and targeted drugs for treatment.
【关键字】:癌,肝细胞;分子生物学;药物释放系统;信号传导
【Key words】:carcinoma, hepatocellular; molecular biology; drug delivery systems; signal transduction
【引证本文】:CHEN WY, REN N. Advances in molecular targeted therapy for hepatocellular carcinoma[J]. J Clin Hepatol, 2018, 34(7): 1387-1394. (in Chinese)
陈万勇, 任宁. 肝细胞癌分子靶向治疗进展[J]. 临床肝胆病杂志, 2018, 34(7): 1387-1394.

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