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【摘要】：中医药辨证论治具有阻断逆转肝纤维化的整体治疗优势，是未来治疗肝纤维化候选药物的源泉。概述了中医药治疗肝纤维化的渊源和现状，重点论述了如何按照循证医学和国际认同的临床试验标准再评价中医药阻断逆转肝纤维化的临床疗效和安全性，介绍了最新临床研究成果。强调了发掘和认同中医药阻断逆转肝纤维化所面临的挑战与重要意义。
【Abstract】：Traditional Chinese medicine (TCM) syndrome differentiation-based treatment has certain advantages in blocking and reversing hepatic fibrosis and is the source of candidate drugs for hepatic fibrosis in future. This article overviews the origin and current status of TCM treatment of hepatic fibrosis, discusses how to reevaluate the clinical effect and safety of TCM in blocking and reversing hepatic fibrosis in accordance with evidence-based medicine and internationally acknowledged standards for clinical trials, and introduces the latest clinical research findings. It also emphasizes the challenge and significance of the exploration and recognition of TCM in blocking and reversing hepatic fibrosis.
【关键字】：肝硬化； 中医学； 中草药； 治疗
【Key words】：liver cirrhosis； TCM science； drugs, Chinese herbal； therapy
【引证本文】：CHEN Y, YANG YP. The role of traditional Chinese medicine in blocking and reversing hepatic fibrosis: current status, hope, and challenge［J］. J Clin Hepatol, 2018, 34(4): 689-693. (in Chinese)
陈艳， 杨永平. 中医药阻断逆转肝纤维化的现状、希望与挑战［J］. 临床肝胆病杂志, 2018, 34(4): 689-693.