首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 3期肝胆胰疾病的内镜诊疗 => 综述 =>血清标志物与瞬时弹性成像技术..
血清标志物与瞬时弹性成像技术评估肝纤维化的研究进展
Research advances in serum markers and transient elastography in the evaluation of liver fibrosis
文章发布日期:2018年02月07日  来源:  作者:许峰铭,盛庆寿  点击次数:611次  下载次数:65次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:肝纤维化及部分早期肝硬化是可逆转的,及时准确地判断肝纤维化程度对慢性肝脏疾病的预防治疗及预后判断具有显著的临床意义。近年来,血清标志物及瞬时弹性成像技术在评估肝纤维化方面已取得较大的进展,介绍了血清学指标及其相关模型对肝纤维化的评估价值,如壳多糖酶3样蛋白1、GP模型、Forns、APRI和FIB-4指数;并简述了瞬时弹性成像检测技术在慢性肝病患者肝纤维化程度分期中的应用进展;认为二者的联合应用对肝纤维化程度的评估有较高的价值。
【Abstract】:Studies have shown that liver fibrosis and some cases of early liver cirrhosis can be reversed, and thus a timely, accurate judgment of fibrosis degree has important clinical significance in prevention/treatment and prognostic evaluation of chronic liver diseases. In recent years, great achievements have been made in the application of serum markers and transient elastography for the evaluation of liver fibrosis. This article introduces the value of serological markers and related models in evaluating liver fibrosis, including CHI3L1, GP model, Forns, APRI, and FIB-4 index, and reviews the advances in the application of transient elastography in determining fibrosis stage in patients with chronic liver diseases. It is pointed out that a combination of these two methods has a high value in evaluating fibrosis degree.
【关键字】:肝硬化; 弹性成像技术; 生物学标记; 诊断; 综述
【Key words】:liver cirrhosis; elasticity imaging techniques; biological markers; diagnosis; review
【引证本文】:XU FM, SHENG QS. Research advances in serum markers and transient elastography in the evaluation of liver fibrosis[J]. J Clin Hepatol, 2018, 34(3): 618-622. (in Chinese)
许峰铭, 盛庆寿. 血清标志物与瞬时弹性成像技术评估肝纤维化的研究进展[J]. 临床肝胆病杂志, 2018, 34(3): 618-622.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号