首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 8期乙型肝炎 => 胰腺疾病 =>高甘油三脂血症相关性急性胰腺炎发病的危险..
高甘油三脂血症相关性急性胰腺炎发病的危险因素分析
Risk factors for hypertriglyceridemia-induced acute pancreatitis
文章发布日期:2017年07月07日  来源:  作者:胡维林  点击次数:163次  下载次数:14次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:目的 探讨高甘油三酯相关性急性胰腺炎发病的相关危险因素,为临床防治提供参考。方法 选取四川省广安市人民医院2014年1月-2016年6月收治的高甘油三酯相关性急性胰腺炎患者42例作为研究组,另选取同期收治的42例非高甘油三酯相关性急性胰腺炎患者(胆源性和酒精性)作为对照组。对两组入选患者就诊时的性别、年龄、合并脂肪肝、BMI、合并2型糖尿病、合并高脂血症、高脂血症家族史、血清甘油三酯、血清胆固醇、LDL、HDL、全血低切黏度、全血高切黏度及D-二聚体浓度等指标进行比较分析。计量资料两组间比较采用t检验;计数资料组间比较采用χ2检验。将单因素分析中有统计学意义的变量再进行多因素非条件logistic回归分析。结果 单因素分析结果显示,性别、合并脂肪肝、BMI、合并2型糖尿病、合并高脂血症、高脂血症家族史、血清甘油三酯水平、全血低切黏度、全血高切黏度及D-二聚体浓度在两组间差异均有统计学意义(P值均<0.05);多因素非条件logistic回归分析显示,合并2型糖尿病[比值比(OR)=2.206,95%可信区间(95%CI):1.125~4.263,P=0.024]、血清甘油三酯水平(OR=5.253,95%CI:2.502~9.568,P=0.001)、BMI(OR=3.812,95%CI:1.896~7.529,P=0.011)、脂肪肝(OR=4255,95%CI:2.185~8.236,P=0.009)及D-二聚体浓度(OR=6.258,95%CI:3.526~11.653,P=0.006)是高甘油三脂相关性急性胰腺炎发病的独立危险因素。结论 对高甘油三酯相关性急性胰腺炎的相关发病高危因素积极进行干预,最大限度降低高脂血症急性胰腺炎的发病率具有重要的临床意义。
【Abstract】:Objective To investigate the risk factors for hypertriglyceridemia-induced acute pancreatitis, and to provide a reference for clinical prevention and treatment. Methods A total of 42 patients with hypertriglyceridemia-induced acute pancreatitis who were admitted to The People′s Hospital of Guang′an from January 2014 to June 2016 were enrolled as study group, and 42 patients with non-hypertriglyceridemia-induced acute pancreatitis (biliary or alcoholic) were enrolled as control group. The two groups were compared in terms of sex, age, fatty liver, body mass index (BMI), type 2 diabetes, hyperlipidemia, family history of hyperlipidemia, serum triglyceride, serum cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), whole blood low-shear viscosity, and D-dimer concentration at the time when they visited the hospital. The t-test was used for comparison of continuous data between groups, and the chi-square test was used for comparison of categorical data between groups. A multivariate non-conditional logistic regression analysis was performed for the statistically significant variables identified in the univariate analysis. Results The univariate analysis showed that there were significant differences between the two groups in sex, fatty liver, BMI, type 2 diabetes, hyperlipidemia, family history of hyperlipidemia, serum triglyceride level, whole blood low-shear viscosity, whole blood high-shear viscosity, and D-dimer concentration (all P<0.05). The multivariate non-conditional logistic regression analysis showed that type 2 diabetes (odds ratio [OR]=2.206, 95% confidence interval [95%CI]: 1.125-4.263, P=0.024), serum triglyceride level (OR=5.253, 95%CI: 2.502-9.568, P=0.001), BMI (OR=3.812, 95%CI: 1.896-7.529, P=0.011), fatty liver (OR=4.255, 95%CI: 2.185-8.236, P=0.009), and D-dimer concentration (OR=6.258, 95%CI: 3.526-11.653, P=0.006) were independent risk factors for hypertriglyceridemia-induced acute pancreatitis. Conclusion It is of great clinical significance to provide intervention for risk factors for hypertriglyceridemia-induced acute pancreatitis and minimize its incidence rate.
【关键字】:胰腺炎;高甘油三酯血症;危险因素
【Key words】:pancreatitis; hypertriglyceridemia; risk factors
【引证本文】:胡维林. 高甘油三脂血症相关性急性胰腺炎发病的危险因素分析[J]. 临床肝胆病杂志, 2017, 33(8): 1518-1521.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号