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射频消融治疗肝细胞癌的机制
Mechanism of radiofrequency ablation in treatment of hepatocellular carcinoma
文章发布日期:2017年01月06日  来源:  作者:王鹏,任卫东  点击次数:1226次  下载次数:387次

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【摘要】:肝细胞癌(HCC)是一种世界范围内发病率和病死率均较高的恶性肿瘤,射频消融(RFA)是一种良好的治疗HCC的方法,尤其适用于肝癌术后复发患者、伴有肝功能不全且不能手术切除和某些多发肝癌患者姑息治疗等,可以明显提高患者的生存时间和生存质量,从直接损伤和间接损伤两个方面综述了RFA治疗HCC的机制,从而进一步理解RFA对肿瘤局部及全身的治疗作用,对今后HCC的多学科联合治疗有潜在价值。
【Abstract】:Hepatocellular carcinoma (HCC) is a malignant tumor with high incidence and mortality rates around the world. Radiofrequency ablation (RFA) is an effective therapy for HCC, especially in patients who experience recurrence after surgery for liver cancer, who are complicated by liver dysfunction and unable to undergo surgical resection, and who have multiple liver tumors and undergo palliative treatment. RFA can significantly improve patients′ survival time and quality of life. This article reviews the mechanism of RFA in the treatment of HCC from the aspects of direct and indirect injuries and helps to further understand the role of RFA in local and systemic treatment of HCC, which has a potential value for multidisciplinary treatment of HCC in future.
【关键字】:肝肿瘤; 癌, 肝细胞; 导管消融术; 综述
【Key words】:liver neoplasms; carcinoma, hepatocellular; catheter ablation; review
【引证本文】:王鹏, 任卫东. 射频消融治疗肝细胞癌的机制[J]. 临床肝胆病杂志, 2017, 33(2): 359-363.

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