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碘-125粒子植入近程放疗在肝胆胰恶性肿瘤中的应用
Clinical effect of brachytherapy with125I seed implantation in treatment of malignant hepatopancreatobiliary tumors
文章发布日期:2016年11月04日  来源:  作者:江旭,杨继金,李慧  点击次数:1165次  下载次数:273次

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【摘要】:碘-125(125I)粒子植入在预防肝癌术后早期复发,联合其他微创治疗方法根治性治疗早期肝癌取得了很好的疗效,同时也广泛应用于中晚期肝癌及门静脉癌栓的治疗。125I粒子用于治疗肝内胆管细胞癌、转移性肝癌等乏血供肿瘤,也取得了很好的局部控制率。125I粒子联合胆道支架可很好的解除恶性胆道梗阻的症状,再狭窄的时间明显延长。基于125I粒子植入的综合介入治疗,能显著改善胰腺癌患者的生活质量并延长生存期。125I粒子植入在临床上使用方便、安全,值得推广。
【Abstract】:Malignant hepatopancreatobiliary tumors are highly malignant and have poor prognosis. 125I seed implantation combined with other minimally invasive therapies for radical treatment of early liver cancer has achieved a good clinical effect in preventing early recurrence after liver cancer surgery. It is also used in the treatment of advanced liver cancer and portal vein tumor thrombosis. 125I seed has achieved a good local control rate in the treatment of tumors with a lack of blood supply, such as intrahepatic cholangiocellular carcinoma and metastatic liver cancer. 125I seed combined with biliary stenting can significantly relieve the symptoms of malignant biliary obstruction and extend the time to restenosis. Comprehensive interventional treatment based on 125I seed can significantly improve quality of life and extend survival time in patients with pancreatic cancer. Therefore, 125I seed implantation is safe and convenient in clinical practice and holds promise for clinical application.
【关键字】:肝肿瘤; 胆管肿瘤; 胰腺肿瘤; 碘放射性同位素; 放射疗法
【Key words】:liver neoplasms; bile duct neoplasms; pancreatic neoplasms; iodine radioisotopes; radiotherapy
【引证本文】:江旭, 杨继金, 李慧. 碘-125粒子植入近程放疗在肝胆胰恶性肿瘤中的应用[J]. 临床肝胆病杂志, 2016, 32(12): 2300-2304.

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