首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2016年 1期 肝癌的介入治疗 => 其他 =>异甘草酸镁注射液与注射用还原型谷..
异甘草酸镁注射液与注射用还原型谷胱甘肽配伍的稳定性分析
Compatible stability of magnesium isoglycyrrhizinate injection and reduced glutathione for injection
文章发布日期:2016年01月12日  来源:  作者:李晓晖,文娱,晋文慧,等  点击次数:1442次  下载次数:241次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】:目的 考察异甘草酸镁(MgIG)注射液与注射用还原型谷胱甘肽(GSH)在室温条件下配伍的稳定性。方法 采用高效液相色谱法测定MgIG注射液与注射用GSH在5%、10%葡萄糖溶液中配伍的浓度变化。结果 MgIG注射液与注射用GSH配伍液在0、0.5、1、1.5、2、4 h内浓度均无明显变化。结论 MgIG注射液与注射用GSH在5%、10%葡萄糖溶液中可以配伍使用,但应在4 h内用完。
【Abstract】:ObjectiveTo evaluate the compatible stability of magnesium isoglycyrrhizinate (MgIG) injection and reduced glutathione (GSH) for injection at room temperature. MethodsHigh-performance liquid chromatography was applied to measure the changes in the content of MgIG and reduced GSH after MgIG injection and reduced GSH for injection were mixed with 5% or 10% glucose solution. ResultsThere were no significant changes in the content of MgIG and reduced GSH within 0, 0.5, 1, 1.5, 2, and 4 h after MgIG injection and reduced GSH for injection were mixed with 5% or 10% glucose solution. ConclusionMgIG injection and reduced GSH for injection are compatible in 5% and 10% glucose solutions, but the mixed solution should be used within 4 h.
【关键字】:异甘草酸镁;谷胱甘肽;中药配伍;药物稳定性
【Key words】:magnesium isoglycyrrhizinate; glutathione; compatibility; drug stability
【引证本文】:李晓晖, 文娱, 晋文慧, 等. 异甘草酸镁注射液与注射用还原型谷胱甘肽配伍的稳定性分析[J]. 临床肝胆病杂志, 2016, 32(1): 143-147.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号