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体素内不相干运动扩散加权成像在肝脏疾病诊疗中的应用
Application of intravoxel incoherent motion diffusion-weighted imaging in liver diseases
文章发布日期:2015年10月14日  来源:  作者:吴琼,付旷,赵荟,等  点击次数:1854次  下载次数:294次

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【摘要】:体素内不相干运动扩散加权成像(IVIM-DWI)不仅可以获得多种参数,还具备同时提供扩散与灌注信息、无需使用对比剂等诸多优势,可以弥补传统扩散加权成像以及对比增强方法的不足。介绍了IVIM-DWI的基本原理及其在包括肝脂肪变、肝纤维化、原发性肝癌、肝局灶性病变等肝脏疾病的诊断、预后估计及治疗方案选择方面的研究进展和临床意义,并总结了IVIM技术在临床应用中遇到的各种挑战,包括b值的确定、数学模型的选择及工作平台条件制约等。分析表明IVIM技术已越来越广泛地应用于临床实践及科学研究,随着设备条件的不断提高与技术问题的进一步解决,IVIM技术将为肝脏病变的准确、快速、无创性评估作出更大的贡献。
【Abstract】:Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) can not only obtain various parameters, but also provide diffusion and perfusion information without contrast agents. IVIM-DWI could make up for the deficiency of traditional DWI and contrast enhancement methods. This paper introduces the basic principle of IVIM-DWI and its research progress and clinical significance in the diagnosis, prognosis, and treatment options for liver diseases, including hepatic steatosis, liver fibrosis, primary liver cancer, and focal liver lesions. This paper also summarizes the challenges confronting the clinical application of IVIM technology, including the determination of b-values, selection of mathematical models, and limitation from working platform conditions. The analyses demonstrate that the IVIM technology has been more and more widely used in clinical practice and scientific research. With continuous improvement in equipment conditions and further solution of technical problems, the IVIM technology will make a greater contribution to the assessment of liver diseases in an accurate, fast, and noninvasive manner.
【关键字】:肝疾病;磁共振成像,弥散;体素内不相干运动
【Key words】:liver diseases; diffusion magnetic resonance imaging; intravoxel incoherent motion
【引证本文】:吴琼, 付旷, 赵荟, 等. 体素内不相干运动扩散加权成像在肝脏疾病诊疗中的应用[J]. 临床肝胆病杂志, 2015, 31(10): 1744-1747.

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