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肝功能异常的评估及临床意义
Evaluation of abnormal liver function and its clinical significance
文章发布日期:2015年09月06日  来源:  作者:李 飞,陆伦根  点击次数:1799次  下载次数:380次

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【摘要】:肝功能异常是肝脏受到致病因素的损害而发生的生化和病理改变,可见于病毒性肝炎、脂肪肝、酒精性肝病、自身免疫性肝病以及其他非肝脏疾病。由于病因复杂,对于少数病例的诊断有时较为困难。归纳了肝脏生化指标在各种肝病中的改变情况以及不同指标联合诊断肝胆疾病的价值。认为肝脏生化检查为肝功能异常的病因诊断提供线索,并进行病情严重程度评估。此外,肝功能异常的病因诊断还有赖于详细的病史采集和体格检查,以及血清学检查、影像学、肝穿刺活组织检查等项目。
【Abstract】:Abnormal liver function is biochemical and pathological changes in the liver caused by damages from pathogens, which can be found in viral hepatitis, fatty liver, alcoholic liver diseases, autoimmune liver diseases, and some non-liver diseases. Due to the diversity in etiology, it is difficult to make a diagnosis for a few cases. This paper summarizes the changes in biochemical indices of the liver due to various liver diseases, and the value of a combination of different indices in the diagnosis of hepatobiliary diseases. This paper concludes that biochemical examination of the liver not only provides hints for the etiological diagnosis of abnormal liver function, but also evaluates the severity of the disease. Moreover, the etiological diagnosis of abnormal liver function also depends on the collection of a detailed history of disease, physical examination, serology, imaging, and liver biopsy.
【关键字】:肝功能不全;转氨酶类;胆红素;诊断,鉴别;综述
【Key words】:hepatic insufficiency; transaminases; bilirubin; diagnosis, differential; review
【引证本文】:李飞, 陆伦根. 肝功能异常的评估及临床意义[J]. 临床肝胆病杂志, 2015, 31(9): 1543-1546.

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