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中心静脉导管引流联合白细胞介素-2注射治疗肝性胸水患者21例疗效观察
Curative effect of central venous catheter in interleukin-2-treated patients with hepatic hydrothorax
文章发布日期:2012年08月14日  来源:  作者:周年兰, 陈超伍, 向晓星  点击次数:1666次  下载次数:482次

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【摘要】:目的观察中心静脉导管引流联合白细胞介素-2(IL-2)注射治疗肝性胸水的疗效。方法40例肝性胸水患者随机分成治疗组(21例)和对照组(19例),两组患者均给予护肝、输白蛋白等支持治疗的基础上,对照组采用常规穿刺抽胸水治疗,治疗组则采用中心静脉导管留置胸腔引流管,完全排空胸水后,注入IL-2,观察两组患者的疗效及并发症情况。结果治疗组治疗总有效率为85.7%,对照组治疗总有效率为52.6%。两组比较差异有统计学意义(P<0.05);治疗组的胸水消退的天数、平均住院费用以及住院天数均明显缩短(P<0.05),并发症少。结论中心静脉导管联合IL-2治疗肝性胸水的疗效显著,值得临床推广。
【Abstract】:ObjectiveTo observe the curative effect of central venous catheter when combined with interleukin (IL)-2 treatment for hepatic hydrothorax. MethodsThirty-three patients with hepatic hydrothorax were randomly assigned to an experimental treatment group (n=17) or a control treatment group (n=16). The experimental group received pleural effusion with continuous drainage by central venous catheter, while the control group was relieved of pleural effusion by conventional puncture. Both groups were administered IL-2 injection into the thoracic cavity after evacuation of pleural effusion. All patients were administered post-operative therapy, including albumin, to protect the liver. The curative effect and complications of two groups were observed. ResultsThe central venous catheter group had a significantly better total effective rate than the conventional puncture control group (82.4% vs 56.3%; P<0.05). The central venous catheter group also had significantly lower duration of pleural effusion persistence, average hospitalization expenses, and duration of hospital stay (P<0.05), as well as experiencing fewer complications. ConclusionThe central venous catheter method for IL-2 intrathoracic treatment produces a good therapeutic effect in patients with hepatic hydrothorax.
【关键字】:导管插入术,中心静脉;白细胞介素-2;胸水;肝硬化
【Key words】:catheterization, central venous; interleukin-2; hydrothorax; liver cirrhosis
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