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恶性梗阻性黄疸双介入疗法的临床应用
Clinical application of double interventional radiology therapy in malignant obstructive jaundice
文章发布日期:2009年10月15日  来源:  作者:张战利; 张焱; 张东超  点击次数:1550次  下载次数:628次

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【摘要】:探讨经皮经肝胆道引流术 (PTCD)及胆道内支架置入术 (PTIBS)并结合动脉持续灌注化疗或栓塞术 (双介入 )治疗恶性梗阻性黄疸的临床意义。 35例恶性梗阻性黄疸患者采用PTCD +PTIBS ,置入内支架术后 2周行局部72小时持续性动脉灌注化疗术或化疗性栓塞术 ,每 4~ 6周一次。 35例采用PTCD +PTIBS均获得成功 ,术后 2周总胆红素从术前 (4 85± 12 0 ) μmol/L降至 (5 4± 30 ) μmol/L ,AKP与ALT均下降明显。 35例患者共施行动脉持续灌注化疗或栓塞 85次 ,随访 10~ 2 4个月 ,半年以上生存率 94 2 % ,支架开通率 85 7% ;一年以上生存率 71 4 % ,支架开通率 74 2 %。PTCD +PTIBS并结合动脉持续灌注化疗或栓塞治疗恶性梗阻性黄疸是安全有效的方法 ,能提高患者的生存质量及延长生存期
【Abstract】:To explore the effect of percutaneous transhepatic cholangiography and drainage (PTCD), percutaneous transhepatic insertion of biliary stents (PTIBS)and combined with continuously infusion arterial chemotherapeutics and chemotherapeutics embolization for treatment of malignant biliary obstruction. 35 patients with malignant obstructive jaundice were treated with PTIBS and after PTIBS 2weeks, performed 72 hours continuously local infusion arterial chemotherapeutics or chemotherapeutics embolization therapy, the period is 4-6 weeks. PTCD and PTIBS was all successful in our 35 cases, The total serum bilirubin decreased obviously, from (485±120) μmol/L before operation to (54±30) μmol/L two weeks after operation, and alkaline phosphatase and transaminase decreased obviously, too. The total eighty-five times continuously infusion arterial chemotherapeutics or chemotherapeutics embolization treatment was performed in 35 patients. All cases were followed up for 10~24 months. The survival rate
【关键字】:恶性梗阻性黄疸; 介入治疗; 内支架; 生存率; 化疗栓塞
【Key words】:malignant obstructive jaundice; interventional therapy; stent; survival rate; chemoembolization
【引证本文】:

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