首 页   本刊简介  编委会  审稿专家  在线期刊  写作规范  广告合作  联系我们
您现在的位置:首页 => 在线期刊 => 2019年 11期“中国肝移植的发展与创新” => 专家论坛 =>儿童肝移植免疫耐受相..
儿童肝移植免疫耐受相关进展
Research advances in immune tolerance in children receiving liver transplantation
文章发布日期:2019年10月25日  来源:  作者:王凯, 高伟  点击次数:212次  下载次数:98次

调整字体大小:

(此处下载失败可以在在线预览处保存副本或者右键另存为)

【摘要】: 相比于成人受者,儿童肝移植受者对于免疫耐受的需求更为迫切,成功实现免疫耐受的概率更高。但目前,在临床上缺乏有效的实验方案、免疫监测手段以及对长期停用免疫抑制剂后移植物组织学的评估,导致免疫耐受长期停留于理论阶段,尚未在临床上有效、广泛开展。通过对儿童肝移植术后免疫耐受在近年来的进展与面临的困难进行简要综述,以期对临床操控性免疫耐受提供一定的帮助。
【Abstract】: Compared with adult recipients, pediatric liver transplantation recipients have urgent needs for immune tolerance, with a higher probability of successful realization of immune tolerance. However at present, there is still a lack of effective experimental regimens, immune monitoring methods, and graft histological evaluation after long-term discontinuation of immunosuppressive agents in clinical practice, which results in the fact that immune tolerance stays in the theoretic stage and is not effectively implemented in clinical practice. This article reviews the advances and difficulties in immune tolerance in pediatric liver transplantation recipients in recent years, in order to provide help for operational immune tolerance in future.
【关键字】:肝移植; 免疫耐受; 儿童
【Key words】:liver transplantation; immune tolerance; child
【引证本文】:WANG K, GAO W. Research advances in immune tolerance in children receiving liver transplantation[J]. J Clin Hepatol, 2019, 35(11): 2402-2407. (in Chinese)
王凯, 高伟. 儿童肝移植免疫耐受相关进展[J]. 临床肝胆病杂志, 2019, 35(11): 2402-2407.

地址:长春市东民主大街519号《临床肝胆病杂志》编辑部 邮编:130061 电话:0431-88782542/3542
临床肝胆病杂志 版权所有 Copyright © 2009 - 2013 Lcgdbzz.org. All Rights Reserv 吉ICP备10000617号

吉公网安备 22010402000041号