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肝细胞癌肝移植术后肿瘤复发的危险因素与防治策略
Risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma and related control strategies
文章发布日期:2019年10月25日  来源:  作者:郑卫萍, 沈中阳  点击次数:204次  下载次数:106次

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【摘要】: 肝细胞癌肝移植术后肿瘤的复发是造成患者和移植物存活率显著下降的主要原因。影响肝移植术后肿瘤复发的危险因素主要包括肿瘤的病理和生物学特性、受者相关因素、供者和供肝相关因素、手术相关因素等。免疫抑制方案的管理以及多种辅助治疗有助于预防肿瘤复发。针对肝细胞癌肝移植患者,如何早期识别肿瘤复发的危险因素并进行综合防治值得进一步探讨。
【Abstract】: Tumor recurrence after liver transplantation for hepatocellular carcinoma is the main cause of significant reductions in the survival rates of patients and grafts. Risk factors for tumor recurrence after liver transplantation include pathological and biological features, factors associated with the recipient, factors associated with the donor and donor liver, and surgery-related factors. Immunosuppression regimen and various adjuvant therapies may help to prevent tumor recurrence. For patients undergoing liver transplantation for hepatocellular carcinoma, further studies are needed to investigate early identification of risk factors for tumor recurrence and related comprehensive prevention and treatment measures.
【关键字】:癌, 肝细胞; 肝移植; 肿瘤复发, 局部; 危险因素; 二级预防
【Key words】:carcinoma, hepatocellular; liver transplantation; neoplasm recurrence, local; risk factors; secondary prevention
【引证本文】:ZHENG WP, SHEN ZY. Risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma and related control strategies[J]. J Clin Hepatol, 2019, 35(11): 2391-2395. (in Chinese)
郑卫萍, 沈中阳. 肝细胞癌肝移植术后肿瘤复发的危险因素与防治策略[J]. 临床肝胆病杂志, 2019, 35(11): 2391-2395.

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