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建立高质量中国证据支持的慢加急性肝衰竭诊断标准和分级诊疗体系
Establishment of the diagnostic criteria and hierarchical diagnosis and treatment system for acute-on-chronic liver failure based on high-quality Chinese evidence
文章发布日期:2019年08月19日  来源:  作者:李海  点击次数:147次  下载次数:43次

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【摘要】:建立一个由中国临床证据支持的慢性肝病急性加重患者分层诊疗体系,以及通过高质量中国循证证据制订适合HBV高流行区慢加急性肝衰竭(ACLF)诊断标准是中国在重肝领域取得突破、发出中国声音的重大机会。以肝脏疾病为原发病伴(肝硬化及非酒精性脂肪性肝炎)及不伴(慢性乙型肝炎非肝硬化)全身器官受损的患者是否可以使用同一种标准诊断ACLF,这是关于制订HBV高流行区ACLF诊断标准的关键。对与欧洲、南美洲慢(加急)性肝衰竭联盟进行全球合作的中国慢(加急)性肝衰竭联盟在上述方面开展的工作进行了介绍。
【Abstract】:Establishment of a hierarchical diagnosis and treatment system for patients with acute exacerbation of chronic liver diseases based on Chinese clinical evidence and development of the diagnostic criteria for acute-on-chronic liver failure (ACLF) in HBV epidemic areas based on high-quality Chinese evidence provide great opportunities for China to make breakthroughs in the field of severe liver diseases and utter the Chinese voice around the world. Whether the same diagnostic criteria for ACLF can be used in patients with liver diseases as primary diseases with (liver cirrhosis and nonalcoholic steatohepatitis) or without (non-cirrhotic chronic hepatitis B) systemic organ injury is the key to the development of the diagnostic criteria for ACLF in HBV epidemic areas. This article introduces the global cooperation between EASL-CLIF Consortium, South America CLIF Consortium, and Chinese CLIF Consortium.
【关键字】:慢加急性肝功能衰竭; 诊断; 参考标准; 临床路径
【Key words】:acute-on-chronic liver failure; diagnosis; reference standards; critical pathways
【引证本文】:LI H. Establishment of the diagnostic criteria and hierarchical diagnosis and treatment system for acute-on-chronic liver failure based on high-quality Chinese evidence[J]. J Clin Hepatol, 2019, 35(9): 1900-1902. (in Chinese)
李海. 建立高质量中国证据支持的慢加急性肝衰竭诊断标准和分级诊疗体系[J]. 临床肝胆病杂志, 2019, 35(9): 1900-1902.

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