Malnutrition in liver cirrhosis: Benefits from improving portal hypertension

Bo GAO; Yuzheng ZHUGE

doi:10.3969/j.issn.1001-5256.2021.12.005

Volume 37 Issue 12

Dec. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(12): 2767-2769

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Malnutrition in liver cirrhosis: Benefits from improving portal hypertension

DOI: 10.3969/j.issn.1001-5256.2021.12.005

Bo GAO^a,
Yuzheng ZHUGE^{b
,
,}

a.
Department of Nutrition, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China
b.
Department of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China

Received Date: 2021-08-04
Accepted Date: 2021-08-31
Published Date: 2021-12-20

Abstract

Abstract

Malnutrition is common in patients with liver cirrhosis, especially with a high incidence rate in the decompensated stage, which mainly manifests as protein-energy malnutrition and has a negative impact on the prognosis of patients. The main causes of malnutrition in liver cirrhosis are insufficient intake and increased consumption. Body composition assessment is an important method to evaluate the type of malnutrition in liver cirrhosis. European Society for Parenteral and Enteral Nutrition (ESPEN) guidelines suggest that Nutritional Risk Screening 2002 (NRS2002) should be used for nutritional risk screening, and cirrhotic patients with an NRS2002 score of ≥3 are considered at the risk of malnutrition. ESPEN guidelines recommend a daily energy intake of 30-35 kcal/kg and a daily protein intake of 1.2-1.5 g/kg for patients with liver cirrhosis. Transjugular intrahepatic portosystemic shunt can effectively reduce portal hypertension in patients with liver cirrhosis and help to improve their nutritional status.
- Liver Cirrhosis,
- Hypertension, Portal,
- Protein-Energy Malnutrition

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References(27)

References

[1]	PARKASH O, JAFRI W, MUNIR SM, et al. Assessment of malnutrition in patients with liver cirrhosis using protein calorie malnutrition (PCM) score verses bio-electrical impedance analysis (BIA)[J]. BMC Res Notes, 2018, 11(1): 545. DOI: 10.1186/s13104-018-3640-y.
[2]	de CARVALHO L, PARISE ER, SAMUEL D. Factors associated with nutritional status in liver transplant patients who survived the first year after transplantation[J]. J Gastroenterol Hepatol, 2010, 25(2): 391-396. DOI: 10.1111/j.1440-1746.2009.06033.x.
[3]	DASARATHY J, ALKHOURI N, DASARATHY S. Changes in body composition after transjugular intrahepatic portosystemic stent in cirrhosis: A critical review of literature[J]. Liver Int, 2011, 31(9): 1250-1258. DOI: 10.1111/j.1478-3231.2011.02498.x.
[4]	CRUZ-JENTOFT AJ, LANDI F, SCHNEIDER SM, et al. Prevalence of and interventions for sarcopenia in ageing adults: A systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS)[J]. Age Ageing, 2014, 43(6): 748-759. DOI: 10.1093/ageing/afu115.
[5]	HUISMAN EJ, TRIP EJ, SIERSEMA PD, et al. Protein energy malnutrition predicts complications in liver cirrhosis[J]. Eur J Gastroenterol Hepatol, 2011, 23(11): 982-989. DOI: 10.1097/MEG.0b013e32834aa4bb.
[6]	KALAITZAKIS E, BJORNSSON E. Hepatic encephalopathy in patients with liver cirrhosis: Is there a role of malnutrition?[J]. World J Gastroenterol, 2008, 14(21): 3438-3439. DOI: 10.3748/wjg.14.3438.
[7]	VIEIRA PM, DE-SOUZA DA, OLIVEIRA LC. Nutritional assessment in hepatic cirrhosis; clinical, anthropometric, biochemical and hematological parameters[J]. Nutr Hosp, 2013, 28(5): 1615-1621. DOI: 10.3305/nh.2013.28.5.6563.
[8]	MAHARSHI S, SHARMA BC, SRIVASTAVA S. Malnutrition in cirrhosis increases morbidity and mortality[J]. J Gastroenterol Hepatol, 2015, 30(10): 1507-1513. DOI: 10.1111/jgh.12999.
[9]	GUGLIELMI FW, PANELLA C, BUDA A, et al. Nutritional state and energy balance in cirrhotic patients with or without hypermetabolism. Multicentre prospective study by the 'Nutritional Problems in Gastroenterology' Section of the Italian Society of Gastroenterology (SIGE)[J]. Dig Liver Dis, 2005, 37(9): 681-688. DOI: 10.1016/j.dld.2005.03.010.
[10]	LEE DH, GIOVANNUCCI EL. Body composition and mortality in the general population: A review of epidemiologic studies[J]. Exp Biol Med (Maywood), 2018, 243(17-18): 1275-1285. DOI: 10.1177/1535370218818161.
[11]	NARANJO-HERNÁNDEZ D, REINA-TOSINA J, ROA LM, et al. Smart bioimpedance spectroscopy device for body composition estimation[J]. Sensors (Basel), 2019, 20(1): 70. DOI: 10.3390/s20010070.
[12]	PROBST P, FUCHS J, SCHÖN MR, et al. Prospective study to evaluate the prognostic value of different nutritional assessment scores in liver surgery: NURIMAS Liver (DRKS00006340)[J]. Hepatobiliary Surg Nutr, 2020, 9(4): 400-413. DOI: 10.21037/hbsn.2019.06.11.
[13]	van VUGT JL, LEVOLGER S, de BRUIN RW, et al. Systematic review and Meta-analysis of the impact of computed tomography-assessed skeletal muscle mass on outcome in patients awaiting or undergoing liver transplantation[J]. Am J Transplant, 2016, 16(8): 2277-2292. DOI: 10.1111/ajt.13732.
[14]	KIM G, KANG SH, KIM MY, et al. Prognostic value of sarcopenia in patients with liver cirrhosis: A systematic review and meta-analysis[J]. PLoS One, 2017, 12(10): e0186990. DOI: 10.1371/journal.pone.0186990.
[15]	XU JY, JIANG ZM. Re-understanding of the concept of nutritional risk from the misunderstanding of 2015 ESPEN consensus statement on diagnostic criteria for malnutrition (undernutrition)[J]. Chin J Clin Nutr, 2016, 24(5): 261-265. DOI: 10.3760/cma.j.issn.1674-635X.2016.05.002. 许静涌, 蒋朱明. 2015年ESPEN营养不良(不足)诊断共识、营养风险及误区[J]. 中华临床营养杂志, 2016, 24(5): 261-265. DOI: 10.3760/cma.j.issn.1674-635X.2016.05.002.
[16]	EGHTESAD S, POUSTCHI H, MALEKZADEH R. Malnutrition in liver cirrhosis: The influence of protein and sodium[J]. Middle East J Dig Dis, 2013, 5(2): 65-75. http://www.tums.ac.ir/1393/04/24/574.pdf-hpoustchi-2014-07-15-10-35.pdf
[17]	PLAUTH M, CABRÉ E, CAMPILLO B, et al. ESPEN guidelines on parenteral nutrition: Hepatology[J]. Clin Nutr, 2009, 28(4): 436-444. DOI: 10.1016/j.clnu.2009.04.019.
[18]	Beijing Medical Association, Committee of Parenteral and Enteral Nutrition; Expert Panel on Consensus on the Parenteral and Enteral Nutritional and the Dietary Intervention for Patients with Chronic Liver Diseases. Consensus on the clinical nutritional intervention for patients with chronic liver diseases[J]. J Clin Hepatol, 2017, 33(7): 1236-1245. DOI: 10.3969/j.issn.1001-5256.2017.07.006. 北京医学会肠外肠内营养学专业委员会, 《慢性肝病患者肠外肠内营养支持与膳食干预专家共识》专家委员会. 慢性肝病患者肠外肠内营养支持与膳食干预专家共识[J]. 临床肝胆病杂志, 2017, 33(7): 1236-1245. DOI: 10.3969/j.issn.1001-5256.2017.07.006.
[19]	LIGUORI I, RUSSO G, ARAN L, et al. Sarcopenia: Assessment of disease burden and strategies to improve outcomes[J]. Clin Interv Aging, 2018, 13: 913-927. DOI: 10.2147/CIA.S149232.
[20]	JEONG JY, LIM S, SOHN JH, et al. Presence of sarcopenia and its rate of change are independently associated with long-term mortality in patients with liver cirrhosis[J]. J Korean Med Sci, 2018, 33(50): e299. DOI: 10.3346/jkms.2018.33.e299.
[21]	KANG SH, JEONG WK, BAIK SK, et al. Impact of sarcopenia on prognostic value of cirrhosis: Going beyond the hepatic venous pressure gradient and MELD score[J]. J Cachexia Sarcopenia Muscle, 2018, 9(5): 860-870. DOI: 10.1002/jcsm.12333.
[22]	NARDELLI S, LATTANZI B, TORRISI S, et al. Sarcopenia is risk factor for development of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt placement[J]. Clin Gastroenterol Hepatol, 2017, 15(6): 934-936. DOI: 10.1016/j.cgh.2016.10.028.
[23]	HANAI T, SHIRAKI M, NISHIMURA K, et al. Sarcopenia impairs prognosis of patients with liver cirrhosis[J]. Nutrition, 2015, 31(1): 193-199. DOI: 10.1016/j.nut.2014.07.005.
[24]	Korean Association for the Study of the Liver (KASL). KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications[J]. Clin Mol Hepatol, 2018, 24(3): 230-277. DOI: 10.3350/cmh.2018.1005.
[25]	CAMCI C, GURAKAR A, KANOSKI M, et al. Nutritional effects of transjugular intrahepatic portosystemic shunt—an often neglected benefit? "A preliminary report"[J]. J Okla State Med Assoc, 2009, 102(1): 10-11. http://www.ncbi.nlm.nih.gov/pubmed/19271637
[26]	STURM L, BETTINGER D, GIESLER M, et al. Treatment with proton pump inhibitors increases the risk for development of hepatic encephalopathy after implantation of transjugular intrahepatic portosystemic shunt (TIPS)[J]. United European Gastroenterol J, 2018, 6(9): 1380-1390. DOI: 10.1177/2050640618795928.
[27]	DASARATHY J, ALKHOURI N, DASARATHY S. Changes in body composition after transjugular intrahepatic portosystemic stent in cirrhosis: A critical review of literature[J]. Liver Int, 2011, 31(9): 1250-1258. DOI: 10.1111/j.1478-3231.2011.02498.x.

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Malnutrition in liver cirrhosis: Benefits from improving portal hypertension

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