Association of circadian rhythm and related genes with nonalcoholic fatty liver disease

Chenlu ZHAO; Wenxia ZHAO

doi:10.3969/j.issn.1001-5256.2021.09.045

Volume 37 Issue 9

Sep. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(9): 2225-2230

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Association of circadian rhythm and related genes with nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.09.045

Chenlu ZHAO¹,
Wenxia ZHAO^{2
,
,}

1.
The First Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou 450016, China
2.
Department of Hepatology and Splee-Stomach, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

Research funding:

General Project of National Natural Science Foundation of China (81473651);

Project of Characteristic Traditional Chinese Medicine Discipline Construction of Henan Province (STG-ZYXKY-2020024)

Received Date: 2021-01-21
Accepted Date: 2021-02-20
Published Date: 2021-09-20

Abstract

Abstract

The association between circadian rhythm and metabolic diseases has attracted more and more attention in recent years. A large number of clinical studies have shown that people who often stay up late or work in shifts have a significantly higher risk of nonalcoholic fatty liver disease than those with regular work and rest. Based on current research findings, this article reviews the mechanism of action of circadian rhythm genes in nonalcoholic fatty liver disease from the five aspects of lipid metabolism, glucose metabolism, intestinal flora, oxidative stress, and endoplasmic reticulum stress.
- Circadian Rhythm,
- Gene,
- Non-alcoholic Fatty Liver Disease

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References(59)

References

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Association of circadian rhythm and related genes with nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2021.09.045

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Association of circadian rhythm and related genes with nonalcoholic fatty liver disease

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