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以重度胆汁淤积为主要表现的弥漫性大B淋巴细胞淋巴瘤1例报告

徐华谦 魏檬 张雪 易海 范方毅 黄爱萍 汤善宏

引用本文:
Citation:

以重度胆汁淤积为主要表现的弥漫性大B淋巴细胞淋巴瘤1例报告

DOI: 10.3969/j.issn.1001-5256.2022.12.025
基金项目: 

四川省卫生健康委员会科研课题 20PJ180

伦理学声明:本例报告已获得患者知情同意。
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:徐华谦参与拟定写作思路,收集分析文献,论文撰写及修改;魏檬、张雪、易海、范方毅、黄爱萍负责病例收集、资料分析、论文修改;汤善宏负责拟定写作思路,指导撰写文章与最后定稿。
详细信息
    通信作者:

    汤善宏,15928956390@163.com

Diffuse large B-cell lymphoma with severe cholestasis as the main manifestation: A case report

Research funding: 

Scientific Research Project of Sichuan Provincial Health Commission 20PJ180

More Information
  • 图  1  腹部CT表现

    注:a,肝、脾肿大,肝脏上下径21.7 cm、前后径18.1 cm、左右径26.1 cm;脾脏上下径18.1 cm、左右径7.7 cm;b,腹腔多发结节影,最大为1.7 cm×1.0 cm。

    Figure  1.  Manifestations of abdominal CT

    图  2  肝穿刺活检病理结果

    注:a,HE染色(×200),可见异常扩大的肝脏汇管区,大量中等偏大的异形淋巴细胞浸润汇管区及肝窦;b,免疫组化CD20(+)(×200);c,免疫组化Ki-67(+80%)(×200)。

    Figure  2.  Pathological results of liver biopsy

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    孙文雄, 李蒲. SOCS3在弥漫大B细胞淋巴瘤患者外周血单个核细胞中的表达及其对OCI-LY7细胞自噬和凋亡的影响[J]. 吉林大学学报(医学版), 2022, 48(1): 172-179. DOI: 10.13481/j.1671-587X.20220121.
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    郭新建, 冶俊玲, 苟笑丹, 等. CD138表达水平对不同免疫表型弥漫大B细胞淋巴瘤患者预后临床价值分析[J]. 临床军医杂志, 2020, 48(1): 72-74. DOI: 10.16680/j.1671-3826.2020.01.21.
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    姚秋艳, 吴泽生, 施荣杰, 等. 以黄疸为表现并发自发性脾破裂的原发性脾淋巴瘤1例报告[J]. 临床肝胆病杂志, 2021, 37(7): 1679-1681. DOI: 10.3969/j.issn.1001-5256.2021.07.042.
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  • 收稿日期:  2022-04-11
  • 录用日期:  2022-05-24
  • 出版日期:  2022-12-20
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