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肝硬化胃食管静脉曲张破裂出血的中西医结合诊疗进展

慕永平

引用本文:
Citation:

肝硬化胃食管静脉曲张破裂出血的中西医结合诊疗进展

DOI: 10.3969/j.issn.1001-5256.2022.09.003
基金项目: 

国家自然科学基金 (81874390)

上海市自然科学基金 (21ZR1464100)

上海市科委“科技创新行动计划”生物医药科技支撑专项 (22S11901700)

上海市临床重点专科建设项目 (shslczdzk01201)

利益冲突声明:作者声明不存在利益冲突。
详细信息
    通信作者:

    慕永平,ypmu8888@126.com

Advances in the integrated traditional Chinese and Western medicine diagnosis and treatment of gastroesophageal variceal bleeding due to liver cirrhosis

Research funding: 

National Natural Science Foundation of China (81874390);

Natural Science Foundation of Shanghai (21ZR1464100);

Special Project for Biomedical Science and Technology Support of "Science and Technology Innovation Action Plan" of Shanghai Science and Technology Commission (22S11901700);

Shanghai Key Specialty of Traditional Chinese Clinical Medicine (shslczdzk01201)

More Information
    Corresponding author: MU Yongping, ypmu8888@126.com(ORCID: 0000-0002-6808-8243)
  • 摘要: 门静脉高压既是肝硬化的结果,又是胃食管静脉曲张的主要原因,一旦发生静脉曲张出血,病情十分凶险,甚至危及患者的生命。因此,如何规范开展内镜筛查,预防首次出血,急诊止血以及预防再次出血等,对胃食管静脉曲张出血的防治至关重要。目前,急诊止血的治疗措施主要包括循环复苏、药物治疗、内镜治疗、介入放射学治疗,以及针对常规治疗可能失败的患者考虑优先经颈静脉肝内门体分流术治疗等。二级预防措施主要包括传统的非选择性β受体阻滞剂或卡维地洛联合内镜下曲张静脉结扎术、经颈静脉肝内门体分流术、球囊阻断逆行静脉栓塞术等。此外,中医药或中西医结合在胃食管静脉曲张出血,尤其是在一级和二级预防领域具有重要作用。本文对近年来中西医结合在肝硬化胃食管静脉曲张出血诊断和治疗方面的研究进展作一简要介绍,以期为临床医生选择合理的诊疗方案提供参考。

     

  • 图  1  GOV的分类[7]

    Figure  1.  Classification of gastroesophageal varices[7]

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    刘平, 胡义扬, 刘成, 等. 扶正化瘀胶囊干预慢性乙型肝炎肝纤维化作用的多中心临床研究[J]. 中西医结合学报, 2003, 1(2): 89-98, 102. https://www.cnki.com.cn/Article/CJFDTOTAL-XBZX200302003.htm
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    陈艳, 杨永平. 中医药阻断逆转肝纤维化的现状、希望与挑战[J]. 临床肝胆病杂志, 2018, 34(4): 689-693. DOI: 10.3969/j.issn.1001-5256.2018.04.002.
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  • 收稿日期:  2022-06-13
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