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Y-box结合蛋白1在慢性肝病发生发展中的作用

刘婷 谢肖立 姜慧卿

刘婷, 谢肖立, 姜慧卿. Y-box结合蛋白1在慢性肝病发生发展中的作用[J]. 临床肝胆病杂志, 2021, 37(11): 2715-2718. DOI: 10.3969/j.issn.1001-5256.2021.11.050
引用本文: 刘婷, 谢肖立, 姜慧卿. Y-box结合蛋白1在慢性肝病发生发展中的作用[J]. 临床肝胆病杂志, 2021, 37(11): 2715-2718. DOI: 10.3969/j.issn.1001-5256.2021.11.050
LIU T, XIE XL, JIANG HQ. Role of Y-box binding protein-1 in the development and progression of chronic liver diseases[J]. J Clin Hepatol, 2021, 37(11): 2715-2718. DOI: 10.3969/j.issn.1001-5256.2021.11.050
Citation: LIU T, XIE XL, JIANG HQ. Role of Y-box binding protein-1 in the development and progression of chronic liver diseases[J]. J Clin Hepatol, 2021, 37(11): 2715-2718. DOI: 10.3969/j.issn.1001-5256.2021.11.050

Y-box结合蛋白1在慢性肝病发生发展中的作用

DOI: 10.3969/j.issn.1001-5256.2021.11.050
基金项目: 

国家自然科学基金面上项目 81770601

河北省研究生创新资助项目 CXZZBS2019121

详细信息
    通讯作者:

    姜慧卿,jianghq@aliyun.com

  • 中图分类号: R575.2;R735.7

Role of Y-box binding protein-1 in the development and progression of chronic liver diseases

Research funding: 

National Natural Science Foundation of China 81770601

Post-graduate's Innovation Fund Project of Hebei Province CXZZBS2019121

  • 摘要: 慢性肝病的病因多种多样,临床长期预后较差。Y-box结合蛋白1系一种多功能蛋白,近年来随着对其研究的深入,发现其在肝纤维化、肝细胞癌等慢性肝脏疾病的发生、发展等过程中均发挥着关键作用。总结了Y-box结合蛋白1在肝纤维化、肝细胞癌(增殖、凋亡、转移、疾病预后和耐药)及肝功能衰竭等慢性肝病中发挥的作用,为慢性肝病的诊治提供一定的理论依据。

     

  • 图  1  YB-1结构域示意图

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  • 收稿日期:  2021-04-02
  • 修回日期:  2021-04-22
  • 网络出版日期:  2021-11-16
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