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甲胎蛋白在肝衰竭患者预后判断中的作用

吴红 李浩 汤善宏

吴红, 李浩, 汤善宏. 甲胎蛋白在肝衰竭患者预后判断中的作用[J]. 临床肝胆病杂志, 2021, 37(11): 2706-2709. DOI: 10.3969/j.issn.1001-5256.2021.11.048
引用本文: 吴红, 李浩, 汤善宏. 甲胎蛋白在肝衰竭患者预后判断中的作用[J]. 临床肝胆病杂志, 2021, 37(11): 2706-2709. DOI: 10.3969/j.issn.1001-5256.2021.11.048
WU H, LI H, TANG SH. Role of alpha-fetoprotein in prognostic evaluation of patients with liver failure[J]. J Clin Hepatol, 2021, 37(11): 2706-2709. DOI: 10.3969/j.issn.1001-5256.2021.11.048
Citation: WU H, LI H, TANG SH. Role of alpha-fetoprotein in prognostic evaluation of patients with liver failure[J]. J Clin Hepatol, 2021, 37(11): 2706-2709. DOI: 10.3969/j.issn.1001-5256.2021.11.048

甲胎蛋白在肝衰竭患者预后判断中的作用

DOI: 10.3969/j.issn.1001-5256.2021.11.048
基金项目: 

四川省卫生健康委员会科研课题 20PJ180

详细信息
    通讯作者:

    汤善宏,shanhongtang@163.com

  • 中图分类号: R575.3

Role of alpha-fetoprotein in prognostic evaluation of patients with liver failure

Research funding: 

Research Project of Sichuan Provincial Health Commission 20PJ180

  • 摘要: 我国是肝病大国,各种肝炎病毒、药物毒物及酒精等都会造成肝损伤,甚至肝衰竭。肝衰竭患者预后的关键在于肝自我修复及再生。甲胎蛋白(AFP)作为肿瘤标志物已在肝癌中得到深入研究,但其在肝衰竭患者肝再生中的研究尚有待深入。总结了AFP在肝再生中的基础研究以及在急性肝衰竭(ALF)和慢加急性肝衰竭(ACLF)中的临床研究,并归纳了本课题组前期研究结果——AFP是HBV相关ACLF后肝再生的重要预后指标及再生因子。经分析表明,继续深入研究AFP在各种肝衰竭中的预后作用以及肝再生中的发生机制,有助于进一步加深对AFP和肝再生的了解,为各种肝衰竭患者的临床诊治和预后评价提供新思路及方法。

     

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  • 收稿日期:  2021-03-31
  • 修回日期:  2021-04-20
  • 网络出版日期:  2021-11-16
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