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circRNA在非酒精性脂肪性肝病诊治中的应用价值

杜晟楠 高静静 汪涛 蒋元烨 曹勤

杜晟楠,高静静,汪涛,等. circRNA在非酒精性脂肪性肝病诊治中的应用价值[J]. 临床肝胆病杂志, 2021, 37(11): 2684-2688. DOI: 10.3969/j.issn.1001-5256.2021.11.043
引用本文: 杜晟楠,高静静,汪涛,等. circRNA在非酒精性脂肪性肝病诊治中的应用价值[J]. 临床肝胆病杂志, 2021, 37(11): 2684-2688. DOI: 10.3969/j.issn.1001-5256.2021.11.043
DU SN, GAO JJ, WANG T, et al. Value of circular RNA in the diagnosis and treatment of nonalcoholic fatty liver disease[J]. J Clin Hepatol, 2021, 37(11): 2684-2688. DOI: 10.3969/j.issn.1001-5256.2021.11.043
Citation: DU SN, GAO JJ, WANG T, et al. Value of circular RNA in the diagnosis and treatment of nonalcoholic fatty liver disease[J]. J Clin Hepatol, 2021, 37(11): 2684-2688. DOI: 10.3969/j.issn.1001-5256.2021.11.043

circRNA在非酒精性脂肪性肝病诊治中的应用价值

DOI: 10.3969/j.issn.1001-5256.2021.11.043
基金项目: 

国家自然科学基金青年项目 81703879

上海市卫计委临床研究专项面上项目 201840377

上海市卫计委临床研究专项面上项目 201940449

普陀区科委自主创新项目 ptkwws201813

上海中医药大学后备卓越中医人才项目 20D-RC-02

详细信息
    通讯作者:

    蒋元烨,yuanye1014@126.com

    曹勤,caoqin434@sina.com

  • 中图分类号: R575.5

Value of circular RNA in the diagnosis and treatment of nonalcoholic fatty liver disease

Research funding: 

National Natural Science Foundation of China 81703879

Shanghai Municipal Commission of Health and Family Planning General Project for Clinical Research of Health Industry 201840377

Shanghai Municipal Commission of Health and Family Planning General Project for Clinical Research of Health Industry 201940449

Putuo District of Shanghai Science And Technology Commission Research Project ptkwws201813

Reserve excellent TCM talents project of Shanghai University of traditional Chinese Medicine 20D-RC-02

  • 摘要: 非酒精性脂肪性肝病(NAFLD)的患病率逐年增加, 目前已成为世界范围内最为常见的慢性肝病之一。研究发现, 环状RNA(circRNA)与NAFLD关系密切,被认为是NAFLD潜在的诊断生物标志物和治疗靶点。归纳了circRNA在NAFLD发病机制中的调控作用及其在诊断和治疗中的价值,指出cirRNA在NAFLD的发生发展进程中扮演着重要角色,并可能在NAFLD的诊断及治疗中具有重要临床意义。

     

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    许胜, 周露玙, 王昆. 环状RNA及其作为疾病标志物的潜能[J]. 中国生物化学与分子生物学报, 2018, 34(2): 117-128. DOI: 10.13865/j.cnki.cjbmb.2018.02.01.
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  • 收稿日期:  2021-03-30
  • 录用日期:  2021-04-28
  • 出版日期:  2021-11-20
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