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雌激素缺乏对绝经后女性非酒精性脂肪性肝病的影响

赵晨露 赵文霞

赵晨露, 赵文霞. 雌激素缺乏对绝经后女性非酒精性脂肪性肝病的影响[J]. 临床肝胆病杂志, 2021, 37(7): 1708-1712. DOI: 10.3969/j.issn.1001-5256.2021.07.049
引用本文: 赵晨露, 赵文霞. 雌激素缺乏对绝经后女性非酒精性脂肪性肝病的影响[J]. 临床肝胆病杂志, 2021, 37(7): 1708-1712. DOI: 10.3969/j.issn.1001-5256.2021.07.049
ZHAO CL, ZHAO WX. Influence of estrogen deficiency on metabolic associated fatty liver disease in postmenopausal women[J]. J Clin Hepatol, 2021, 37(7): 1708-1712. DOI: 10.3969/j.issn.1001-5256.2021.07.049
Citation: ZHAO CL, ZHAO WX. Influence of estrogen deficiency on metabolic associated fatty liver disease in postmenopausal women[J]. J Clin Hepatol, 2021, 37(7): 1708-1712. DOI: 10.3969/j.issn.1001-5256.2021.07.049

雌激素缺乏对绝经后女性非酒精性脂肪性肝病的影响

DOI: 10.3969/j.issn.1001-5256.2021.07.049
基金项目: 

国家自然科学基金面上项目 81473651

河南省科技攻关计划项目 202102310495

详细信息
    通讯作者:

    赵文霞, zhao_wenxia@163.com

  • 中图分类号: R575.5

Influence of estrogen deficiency on metabolic associated fatty liver disease in postmenopausal women

Funds: 

National Natural Science Foundation of China(General Program) 81473651

Science and Technology Key Project of Henan Province 202102310495

  • 摘要: 流行病学数据显示, 绝经后女性非酒精性脂肪性肝病(NAFLD)的发病率显著高于绝经前女性和同龄期男性。针对这一临床现象, 重点从胰岛素抵抗、肝脂质代谢、肝纤维化和肠道菌群四个方面总结了雌激素缺乏对绝经后女性NAFLD潜在的影响机制, 为绝经后女性NAFLD的早期临床防治提供参考。

     

  • 图  1  各年龄段NAFLD患病人群中的男女比例

    图  2  雌激素缺乏对绝经后女性NAFLD的作用机制

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  • 收稿日期:  2020-11-18
  • 修回日期:  2021-01-05
  • 刊出日期:  2021-07-20
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