糖代谢紊乱对肝硬化相关并发症的影响

田彩云; 胡晗; 张国远; 林世德

doi:10.3969/j.issn.1001-5256.2021.05.046

糖代谢紊乱对肝硬化相关并发症的影响

DOI: 10.3969/j.issn.1001-5256.2021.05.046

遵义医科大学附属医院感染科，贵州遵义 563003

基金项目:

国家自然科学基金 (81860114)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：田彩云负责课题设计，资料分析，撰写论文；胡晗、张国远参与收集数据，修改论文；林世德负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

作者简介:
田彩云(1995—)，女，主要从事肝脏与糖代谢相关研究

通信作者:
林世德，linshide6@hotmail.com

中图分类号: R575.2
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- 文章访问数: 405
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- 被引次数: 0
出版历程
- 收稿日期: 2020-11-06
- 录用日期: 2020-12-04
- 出版日期: 2021-05-20

Influence of glucose metabolism disorder on complications associated with liver cirrhosis

Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China

摘要

摘要: 糖尿病与肝硬化在全球范围内均有较高的发病率及死亡率，近十年国内外学者对两者的相关性作了大量研究。系统综述了近十年国内外在糖尿病对肝硬化及相关并发症影响方面的基础和临床研究进展，并对其可能的机制进行了总结。结果表明糖尿病可加速肝纤维化进程，增加肝硬化患者相关并发症及其进展为肝癌的风险，降低其生存率。
- 肝硬化 /
- 糖尿病 /
- 胰岛素抵抗
Abstract: Both diabetes mellitus and liver cirrhosis have high incidence rate and mortality rate around the world, and in recent ten years, scholars in China and globally have conducted many studies on the association between diabetes mellitus and liver cirrhosis. This article systematically reviews the advances in the basic and clinical research on the influence of diabetes mellitus on liver cirrhosis and its complications and summarizes possible mechanisms. The results show that diabetes mellitus can accelerate the process of liver fibrosis, increase the risk of complications and progression to liver cancer in patients with liver cirrhosis, and reduce their survival rate.
- Liver Cirrhosis /
- Diabetes Mellitus /
- Insulin Resistance

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参考文献(51)

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