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microRNA-125b在多种慢性肝病发生发展中的作用

卢能源 王佳慧 钟芳菲 汪磊 彭岳 赵铁建 郑洋

卢能源, 王佳慧, 钟芳菲, 等. microRNA-125b在多种慢性肝病发生发展中的作用[J]. 临床肝胆病杂志, 2021, 37(3): 725-728. DOI: 10.3969/j.issn.1001-5256.2021.03.046
引用本文: 卢能源, 王佳慧, 钟芳菲, 等. microRNA-125b在多种慢性肝病发生发展中的作用[J]. 临床肝胆病杂志, 2021, 37(3): 725-728. DOI: 10.3969/j.issn.1001-5256.2021.03.046
LU NY, WANG JH, ZHONG FF, et al. Role of microRNA-125b in the development and progression of various chronic liver diseases [J]. J Clin Hepatol, 2021, 37(3): 725-728. DOI: 10.3969/j.issn.1001-5256.2021.03.046
Citation: LU NY, WANG JH, ZHONG FF, et al. Role of microRNA-125b in the development and progression of various chronic liver diseases [J]. J Clin Hepatol, 2021, 37(3): 725-728. DOI: 10.3969/j.issn.1001-5256.2021.03.046

microRNA-125b在多种慢性肝病发生发展中的作用

DOI: 10.3969/j.issn.1001-5256.2021.03.046
基金项目: 

国家自然科学基金 81660705

国家自然科学基金 81960751

国家自然科学基金 81960761

广西自然基金 2020JJB140144

广西自然基金 2020JJA140257

广西中青年教师科研基础能力提升项目 2020KY59009

广西壮瑶药重点实验室 GXZYZZ2019-1

广西壮瑶药重点实验室 GXZYZZ2020-07

广西中医药大学一流学科 2019XK141

广西中医药大学赛恩斯新医药学院院级课题 2019ZD03

广西中医药大学校级课题青年基金 2020QN006

广西中医药大学赛恩斯新医药学院大学生创新创业训练项目(国家级) 202013643009

广西中医药大学赛恩斯新医药学院大学生创新创业训练项目(国家级) 202013643014

广西中医药大学赛恩斯新医药学院大学生创新创业训练项目(自治区级) 202013643027

广西中医药大学赛恩斯新医药学院大学生创新创业训练项目(自治区级) 202013643032

详细信息
    作者简介:

    卢能源(2000—),男,主要从事民族药防治慢性肝病相关研究

    通讯作者:

    郑洋,1793853705@qq.com

  • 利益冲突声明:所有作者均声明不存在利益冲突。
  • 作者贡献声明:卢能源负责文献检索, 文章思路设计, 论文撰写与修订;王佳慧、钟芳菲、汪磊、彭岳负责文献检索与资料分析;,赵铁建、郑洋负责指导撰写文章及最后定稿。
  • 中图分类号: R575

Role of microRNA-125b in the development and progression of various chronic liver diseases

  • 摘要: 微小RNA(miRNA)是一类非编码的小分子RNA,是基因表达的转录后调控因子。简述了多种慢性肝病,包括代谢功能障碍相关性脂肪性肝病、慢性乙型肝炎、慢性丙型肝炎、慢性药物性肝损伤、肝硬化以及肝细胞癌的相关病因,归纳了近年来关于miR-125b通过靶向不同的靶基因,进入不同的信号转导途径而在同一肝病或病理进程中发挥着相同或相悖的调控作用的相关报道,以期为多种慢性肝病的发病机制研究和非创伤性鉴别手段的建立提供相关见解。
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  • 收稿日期:  2020-09-05
  • 修回日期:  2020-10-30
  • 刊出日期:  2021-03-16
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