移植肿瘤学开创肝移植治疗肝癌新时代

韩承祚; 卫强; 徐骁

doi:10.3969/j.issn.1001-5256.2021.02.002

移植肿瘤学开创肝移植治疗肝癌新时代

DOI: 10.3969/j.issn.1001-5256.2021.02.002

浙江大学医学院附属杭州市第一人民医院肝胆胰外科，杭州 310006

基金项目:

国家自然科学基金 (81930016);

国家自然科学基金 (81625003);

浙江省重点研发计划 (2019C03050);

浙江省重点研发计划 (2021C03118)

作者贡献声明：韩承祚负责文献检索和撰写论文；卫强负责撰写及修改论文；徐骁负责拟定写作思路、指导撰写文章并最后定稿。

详细信息

作者简介:
韩承祚(1996—)，女，主要从事肝胆胰外科和器官移植研究

通信作者:
徐骁，zjxu@zju.edu.cn

中图分类号: R735.7;R617
计量
- 文章访问数: 492
- HTML全文浏览量: 123
- PDF下载量: 60
- 被引次数: 0
出版历程
- 收稿日期: 2020-11-23
- 录用日期: 2020-12-23
- 出版日期: 2021-02-20

Transplant oncology creates a new era of liver transplantation for the treatment of liver cancer

Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China

摘要

摘要: 近年来，外科学、肿瘤学、免疫学、药学和影像学等深度交叉融合，逐渐形成了新兴学科——移植肿瘤学。随着移植肿瘤学的发展，肝移植在肝胆胰恶性肿瘤的治疗中发挥了越来越关键的作用。回溯移植肿瘤学的发展并总结其特点，重点阐述移植肿瘤学发展在肝癌精准诊治，尤其是肝癌肝移植受者选择、供肝来源拓展中发挥的重要作用，强调肝癌肝移植术后肿瘤复发防治及其机制的探索仍是移植肿瘤学研究的重点攻关方向。
- 肝肿瘤 /
- 肝移植 /
- 治疗学
Abstract: In recent years, the integration of surgery, oncology, immunology, pharmacology, and imaging has gradually formed the new discipline of transplant oncology. With the development of transplant oncology, liver transplantation plays an increasingly important role in the treatment of hepatobiliary and pancreatic malignant tumors. This article reviews the evolution of transplant oncology and summarizes its characteristics, and particularly elaborates on the important role of transplant oncology in the precise treatment of liver cancer, especially the selection of recipients and expansion of the source of donor liver. It is highlighted that the prevention and treatment of tumor recurrence after liver transplantation for liver cancer and exploration of related mechanisms are still the major research directions in transplant oncology.
- Liver Neoplasms /
- Liver Transplantation /
- Therapeutics

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参考文献(30)

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