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中华医学会, 中华医学会杂志社, 中华医学会消化病学分会, 等. 酒精性肝病基层诊疗指南(2019年)[J]. 临床肝胆病杂志, 2021, 37(1): 36-40. DOI: 10.3969/j.issn.1001-5256.2021.01.008
引用本文: 中华医学会, 中华医学会杂志社, 中华医学会消化病学分会, 等. 酒精性肝病基层诊疗指南(2019年)[J]. 临床肝胆病杂志, 2021, 37(1): 36-40. DOI: 10.3969/j.issn.1001-5256.2021.01.008
Chinese Medical Association; Chinese Medical Journals Publishing House; Chinese Society of Gastroenterol-ogy, Chinese Medical Association, et al. Guideline for prima-ry care of alcoholic liver disease (2019)[J]. J Clin Hepatol, 2021, 37(1): 36-40. DOI: 10.3969/j.issn.1001-5256.2021.01.008
Citation: Chinese Medical Association; Chinese Medical Journals Publishing House; Chinese Society of Gastroenterol-ogy, Chinese Medical Association, et al. Guideline for prima-ry care of alcoholic liver disease (2019)[J]. J Clin Hepatol, 2021, 37(1): 36-40. DOI: 10.3969/j.issn.1001-5256.2021.01.008

酒精性肝病基层诊疗指南(2019年)

DOI: 10.3969/j.issn.1001-5256.2021.01.008
详细信息
  • 利益冲突声明:所有作者均声明不存在利益冲突
  • 通信作者:刘玉兰,liuyulan@pkuph.edu.cn;王江滨,zrlwangjb@163.com
  • 中图分类号: R575

  • 表  1  酒精使用障碍量表测试(AUDIT)

    问题 评分(分)
    0 1 2 3 4
    1.你喝酒的次数是多少? 从不 约1次/月 2~4次/月 2~3次/周 >4次/周
    2.在喝酒的那一天中所饮的酒量是多少“杯”? 1或2 3或4 5或6 7~9 >10
    3.每次喝6“杯”以上的次数为多少? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    4.是否一开始喝酒就无法立即中断?这种情况在最近1年中有几次? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    5.你有没有因为喝酒而耽误要做的事情?这种情况在最近1年中有几次? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    6.在一次大量饮酒后,你是否需要在次日早上喝一些酒才能正常生活?这种情况在最近1年中有几次? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    7.你会不会在饮酒之后感到内疚或后悔?这种情况在最近1年中有几次? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    8.你会不会因为喝酒而回忆不起来前夜所发生的情况?这种情况在最近1年中有几次? 从不 <1次/月 1次/月 几乎1次/周 1次/d或几乎1次/d
    9.有没有因为你喝酒而使本人或他人受到损伤的情况?这种情况在最近1年中有几次? 没有 - 有,但不在
    过去的1年
    - 有,是在过去的1年
    10.你的亲戚好友、医生或其他卫生工作者有没有关心过你的饮酒问题,并劝过你戒酒? 没有 - 有,但不在
    过去的1年
    - 有,是在过去的1年
    注:饮酒中含有酒精10 g为1杯;总评分≥8分为阳性,仅前3个问题高分(≥3分)提示严重危害性饮酒;问题4、5、6高分(≥3分)表示酒精依赖;最后4题高分(≥3分)说明饮酒有伤害;“-”,表示无。
    下载: 导出CSV
  • [1] National Workshop on Fatty Liver and Alcoholic Liver Disease, Chinese Society of Hepatology, Chinese Medical Association; Fatty Liver Expert Committee, Chinese Medical Doctor Association.Guidelines of prevention and treatment for alcoholic liver disease:A 2018 update[J]. J Clin Hepatol, 2018, 34(5): 939-946.(in Chinese) DOI: 10.3969/j.issn.1001-5256.2018.05.006

    中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会. 酒精性肝病防治指南(2018年更新版)[J]. 临床肝胆病杂志, 2018, 34(5): 939-946. DOI: 10.3969/j.issn.1001-5256.2018.05.006
    [2] Alcohol Dependence and Liver Disease Investigation Cooperation Group.Collaborative study on alcohol dependence among 4 occupational populations in 9 cities in China (1): Methodology and prevalence[J]. Chin Mental Health J, 1992, 6(3): 112-115.(in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS199203006.htm

    酒依赖与肝病问题调查协作组. 中国9个城市4种职业人群酒依赖协作研究(一): 方法学及患病率[J]. 中国心理卫生杂志, 1992, 6(3): 112-115. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS199203006.htm
    [3] CHEN SL, MENG XD, WANG BY, et al. An epidemiologic survey of alcoholic liver disease in some cities of Liaoning Province[J]. J Prac Hepatol, 2010, 13(6): 428-430, 435.(in Chinese) DOI: 10.3969/j.issn.1672-5069.2010.06.010

    陈士林, 孟晓丹, 王炳元, 等. 辽宁省部分城市酒精性肝病流行现状调查[J]. 实用肝脏病杂志, 2010, 13(6): 428-430, 435. DOI: 10.3969/j.issn.1672-5069.2010.06.010
    [4] LI YM, CHEN WX, YU ZH, et al. An epidemiological survey of alcoholic liver disease in Zhejiang province[J]. Chin J Hepatol, 2003, 11(11): 647-649.(in Chinese) DOI: 10.3760/j.issn:1007-3418.2003.11.002

    厉有名, 陈卫星, 虞朝辉, 等. 浙江省酒精性肝病流行病学调查概况[J]. 中华肝脏病杂志, 2003, 11(11): 647-649. DOI: 10.3760/j.issn:1007-3418.2003.11.002
    [5] YAN H, LU XL, GAO YQ, et al. Epidemiological investigation of fatty liver disease in Northwest China[J]. Chin J Hepatol, 2015, 23(8): 622-627.(in Chinese) DOI: 10.3760/cma.j.issn.1007-3418.2015.08.013

    延华, 鲁晓岚, 高艳琼, 等. 西北地区脂肪性肝病的流行病学调查研究[J]. 中华肝脏病杂志, 2015, 23(8): 622-627. DOI: 10.3760/cma.j.issn.1007-3418.2015.08.013
    [6] WANG H, MA L, YIN Q, et al. Prevalence of alcoholic liver disease and its association with socioeconomic status in north-eastern China[J]. Alcohol Clin Exp Res, 2014, 38(4): 1035-1041. DOI: 10.1111/acer.12321
    [7] National Alcoholic Liver Disease Investigation Cooperation Group.Management of malignant biliary hilar obstruction with multiple stents[J]. Chin J Dig, 2007, 27(4): 231-234.(in Chinese) DOI: 10.3760/j.issn:0254-1432.2007.04.005

    全国酒精性肝病调查协作组. 全国酒精性肝病的多中心调查分析[J]. 中华消化杂志, 2007, 27(4): 231-234. DOI: 10.3760/j.issn:0254-1432.2007.04.005
    [8] REHM J, TAYLOR B, MOHAPATRA S, et al. Alcohol as a risk factor for liver cirrhosis:A systematic review and meta-analysis[J]. Drug Alcohol Rev, 2010, 29(4): 437-445. DOI: 10.1111/j.1465-3362.2009.00153.x
    [9] TIAN LY, LU LG.2012 European Society of Hepatology clinical practice guidelines: Treatment of alcoholic liver disease[J/CD]. Chin J Front Med Sci (Electronic Version), 2012, 4(9): 64-71.(in Chinese)

    田丽艳, 陆伦根. 2012欧洲肝病学会临床实践指南: 酒精性肝病的治疗[J/CD]. 中国医学前沿杂志(电子版), 2012, 4(9): 64-71.
    [10] VIDAL F, LORENZO A, AUGUET T, et al. Genetic polymorphisms of ADH2, ADH3, CYP4502E1 Dra-I and Pst-I, and ALDH2 in Spanish men:Lack of association with alcoholism and alcoholic liver disease[J]. J Hepatol, 2004, 41(5): 744-750. DOI: 10.1016/j.jhep.2003.06.003
    [11] National Workshop on Fatty Liver and Alcoholic Liver Disease, Chinese Society of Hepatology, Chinese Medical Association.Guidelines for diagnosis and treatment of nonalcoholic fatty liver diseases[J]. Mod Digest Interv, 2007, 12(4): 266-268.(in Chinese) DOI: 10.3969/j.issn.1672-2159.2007.04.020

    中华医学会肝脏病学分会脂肪肝和酒精性肝病学组. 非酒精性脂肪性肝病诊疗指南[J]. 现代消化及介入诊疗, 2007, 12(4): 266-268. DOI: 10.3969/j.issn.1672-2159.2007.04.020
    [12] LI Y, JIANG Y, ZHANG M, et al. Drinking behaviour among men and women in China:The 2007 China chronic disease and risk factor surveillance[J]. Addiction, 2011, 106(11): 1946-1956. DOI: 10.1111/j.1360-0443.2011.03514.x
    [13] SABERI B, DADABHAI AS, JANG YY, et al. Current management of alcoholic hepatitis and future therapies[J]. J Clin Transl Hepatol, 2016, 4(2): 113-122.
    [14] SINGH S, OSNA NA, KHARBANDA KK.Treatment options for alcoholic and non-alcoholic fatty liver disease:A review[J]. World J Gastroenterol, 2017, 23(36): 6549-6570. DOI: 10.3748/wjg.v23.i36.6549
    [15] NGUYEN-KHAC E, THEVENOT T, PIQUET MA, et al. Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis[J]. N Engl J Med, 2011, 365(19): 1781-1789. DOI: 10.1056/NEJMoa1101214
    [16] MORENO C, DELTENRE P, SENTERRE C, et al. Intensive enteral nutrition is ineffective for patients with severe alcoholic hepatitis treated with corticosteroids[J]. Gastroenterology, 2016, 150(4): 903-910. DOI: 10.1053/j.gastro.2015.12.038
    [17] BJÖRNSSON E, OLSSON J, RYDELL A, et al. Long-term follow-up of patients with alcoholic liver disease after liver transplantation in Sweden:Impact of structured management on recidivism[J]. Scand J Gastroenterol, 2005, 40(2): 206-216. DOI: 10.1080/00365520410009591
    [18] MORLEY KC, BAILLIE A, FRASER I, et al. Baclofen in the treatment of alcohol dependence with or without liver disease:Multisite, randomised, double-blind, placebo-controlled trial[J]. Br J Psychiatry, 2018, 212(6): 362-369. DOI: 10.1192/bjp.2018.13
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  • 收稿日期:  2020-11-25
  • 修回日期:  2020-11-25
  • 刊出日期:  2021-01-18
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