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前列腺素E1辅助治疗轻中度急性胰腺炎的临床分析

纪柏 陈丽宇 刘亚辉

纪柏, 陈丽宇, 刘亚辉. 前列腺素E1辅助治疗轻中度急性胰腺炎的临床分析[J]. 临床肝胆病杂志, 2016, 32(1): 123-126. DOI: 10.3969/j.issn.1001-5256.2016.01.023
引用本文: 纪柏, 陈丽宇, 刘亚辉. 前列腺素E1辅助治疗轻中度急性胰腺炎的临床分析[J]. 临床肝胆病杂志, 2016, 32(1): 123-126. DOI: 10.3969/j.issn.1001-5256.2016.01.023
Ji Bo, Chen LiYu, Liu YaHui. Efficacy of prostaglandin E1 as adjuvant therapy for mild to moderate acute pancreatitis[J]. J Clin Hepatol, 2016, 32(1): 123-126. DOI: 10.3969/j.issn.1001-5256.2016.01.023
Citation: Ji Bo, Chen LiYu, Liu YaHui. Efficacy of prostaglandin E1 as adjuvant therapy for mild to moderate acute pancreatitis[J]. J Clin Hepatol, 2016, 32(1): 123-126. DOI: 10.3969/j.issn.1001-5256.2016.01.023

前列腺素E1辅助治疗轻中度急性胰腺炎的临床分析

DOI: 10.3969/j.issn.1001-5256.2016.01.023
详细信息
  • 中图分类号: R576

Efficacy of prostaglandin E1 as adjuvant therapy for mild to moderate acute pancreatitis

  • 摘要: 目的对比观察前列腺素E1在治疗急性胰腺炎(AP)中的临床疗效和安全性。方法前瞻性研究2014年5月-2015年1月吉林大学第一医院收治的轻中度AP患者80例,随机分为2组。对照组44例行胰腺炎常规综合治疗,试验组36例在常规治疗基础上加用前列腺素E1。比较2组患者腹部症状消失时间、血尿淀粉酶、血清脂肪酶、C反应蛋白、降钙素原降至正常水平的时间。计量资料组间比较采用独立样本t检验;计数资料组间比较采用χ2检验或Fisher精确检验。结果 2组血淀粉酶、C反应蛋白、中性粒细胞百分比恢复正常值的时间及住院费用间差异均有统计学意义(P值分别为0.041、0.030、0.012、0.026)。前列腺素E1可明显加速缓解腹痛、腹胀,快速降低血淀粉酶、C反应蛋白和中性粒细胞百分比;缩短住院时间,减少住院费用。结论前列腺素E1在治疗胰腺炎中具有良好的临床疗效、安全性好,可作为胰腺炎药物综合治疗的辅助用药选择。

     

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  • 收稿日期:  2015-07-01
  • 刊出日期:  2016-01-20
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