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磁共振扩散加权成像对经皮酒精注射术治疗兔VX2肝移植瘤后残余肿瘤微血管生成情况的评价

陈娟 尹化斌 张欢欢 魏春晓 王丽 钱亭

陈娟, 尹化斌, 张欢欢, 魏春晓, 王丽, 钱亭. 磁共振扩散加权成像对经皮酒精注射术治疗兔VX2肝移植瘤后残余肿瘤微血管生成情况的评价[J]. 临床肝胆病杂志, 2016, 32(1): 101-105. DOI: 10.3969/j.issn.1001-5256.2016.01.018
引用本文: 陈娟, 尹化斌, 张欢欢, 魏春晓, 王丽, 钱亭. 磁共振扩散加权成像对经皮酒精注射术治疗兔VX2肝移植瘤后残余肿瘤微血管生成情况的评价[J]. 临床肝胆病杂志, 2016, 32(1): 101-105. DOI: 10.3969/j.issn.1001-5256.2016.01.018
Chen Juan, Yin HuaBin, Zhang HuanHuan, Wei ChunXiao, Wang Li, Qian Ting. Diffusion-weighted magnetic resonance imaging for evaluation of micro-angiogenesis in residual tumor after treatment with percutaneous ethanol injection in a rabbit VX2 liver tumor model[J]. J Clin Hepatol, 2016, 32(1): 101-105. DOI: 10.3969/j.issn.1001-5256.2016.01.018
Citation: Chen Juan, Yin HuaBin, Zhang HuanHuan, Wei ChunXiao, Wang Li, Qian Ting. Diffusion-weighted magnetic resonance imaging for evaluation of micro-angiogenesis in residual tumor after treatment with percutaneous ethanol injection in a rabbit VX2 liver tumor model[J]. J Clin Hepatol, 2016, 32(1): 101-105. DOI: 10.3969/j.issn.1001-5256.2016.01.018

磁共振扩散加权成像对经皮酒精注射术治疗兔VX2肝移植瘤后残余肿瘤微血管生成情况的评价

DOI: 10.3969/j.issn.1001-5256.2016.01.018
详细信息
  • 中图分类号: R445.2;R735.7

Diffusion-weighted magnetic resonance imaging for evaluation of micro-angiogenesis in residual tumor after treatment with percutaneous ethanol injection in a rabbit VX2 liver tumor model

  • 摘要:

    目的研究磁共振扩散加权成像(DWI)评价兔VX2肝移植瘤模型经皮酒精注射术(PEI)疗效及PEI对残余肿瘤微血管生成的影响。方法将26只接种成功的兔VX2肝移植瘤模型随机分为实验组和对照组,每组各13只。实验组CT引导下行PEI,对照组不予处理,术后1周行DWI检查,比较实验组肿瘤活性区及坏死区表观弥散系数(ADC)的差异、2组活性肿瘤区ADCperf和微血管密度(MVD)计数的差异,并分析ADCperf与MVD计数的相关性。正态性分析采用Shapiro-Wilk检验,计量资料组间比较采用Wilcoxon秩和检验,ADCperf与MVD计数的相关性比较采用Pearson相关分析。结果实验组坏死区与活性肿瘤区ADCtotal值分别为[1.674(1.3402.571)]×10-3mm2/s、[1.296(1.1201.972)]×10-3mm2/s,差异有统计学意义(Z=2.052,P=0.040);实验组与对照组活性肿瘤区ADCperf值分别为[0.568(0.3811.873)]×10-3mm2/s、[0.947(0....

     

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  • 收稿日期:  2015-08-24
  • 刊出日期:  2016-01-20
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