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加藤直野
Associate Professor
Unit of Disease Control Genome Medicine
个人简介:
    加藤直野,男,1962年生人,日本籍,东京大学医学科学研究所副教授。主要研究乙型肝炎,丙型肝炎,肝癌分子生物学,遗传学等。
发表论文及科研的基本情况:
1. Chang J-H, Kato N, Muroyama R, Taniguchi H, Guleng B, Dharel N, Shao R-X, Tateishi K, Jazag A, Kawabe T, Omata M. Double-stranded-RNA-activated protein kinase inhibits hepatitis C virus replication but may be not essential in interferon treatment. Liver Int 2010; 30: 311-318
2. Hu Z, Muroyama R, Kowatari N, Chang J, Omata M, Kato N. Characteristic mutations in hepatitis C virus core gene related to the occurrence of hepatocellular carcinoma. Cancer Sci 2009; 100: 2465-2468.
3. Omata M, Yoshida H, Shiina S, Kato N. Hepatocellular carcinoma “epidemics” in Japan. In: Karayiannis P, Main J, Thomas H eds. Hepatitis C virus. International Medical Press Ltd. 2009: 5.1-5.10.
4. Masuzaki R, Tateishi R, Yoshida H, Yoshida H, Sato S, Kato N, Kanai F, Sugioka Y, Ikeda H, Shiina S, Kawabe T, Omata M. Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography. Hepatology 2009; 49: 1954-1961.
5. Li C-Z, Kato N, Chang J-H, Muroyama R, Shao R-X, Dharel N, Sermsathanasawadi R, Kawabe T, Omata M. Polymorphism of OAS-1 determines liver fibrosis progression in hepatitis C by reduced ability to inhibit viral replication. Liver Int 2009; 29: 1413-1421. 6. Dharel N, Kato N, Muroyama R, Taniguchi H, Otsuka M, Wang Y, Jazag A, Shao R-X, Chang J-H, Adler MK, Kawabe T, Omata M. Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus. Hepatology 2008; 47: 1136-1149.
7.Sermasathanasawadi R, Kato N, Muroyama R, Dharel N, Shao R-X, Chang J-H, Li C-Z, Kawabe T, Omata M. Association of IRF-7 gene polymorphism with liver cirrhosis in chronic hepatitis C patients. Liver Int 2008; 28: 798-806
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