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孙兆黎
博士
Johns Hopkins University School of Medicine

个人简介:
1984-1989    白求恩医科大学医学一系,医学学士
1989-1991    白求恩医科大学第一医院小儿外科,医师
1991-1994    白求恩医科大学第一医院, 外科学硕士 (1994年晋升主治医师)
1994-1997    白求恩医科大学,免疫学博士
1997-2000    Johns Hopkins大学医学院外科博士后
2000-2003    Johns Hopkins大学医学院外科讲师 (Instructor)
2003-2010    Johns Hopkins大学医学院外科 助理教授 (Assistant Professor)
2010-            Johns Hopkins大学医学院外科 副教授 (Associate Professor)
发表论文及科研的基本情况:
Selected publications:
1.Zhaoli Sun, Andrew S. Klein, Osama EL-Assal, Svetlana Radaeva, Sandor Batkai, Zhaigan Tian, Sumito Hoshino, Anna Mae Diehl, Bin Gao. Interlukin-6 in vitro treatment prevents mortality associated with fatty liver transplant in rats. Gastroenterology, 2003 July 125: 202-215.
2.Zhaoli Sun, Tatehiko Wada, Keiichiro Uchikura, Sumito Hoshino, Kosei Meamura, Anna Mae Diehl, Andrew S. Klein. Hepatic Allograft-derived Kupffer cells regulate T cell response in rats. Liver Transplantation, 2003;9(5):489-497
3.Keiichiro Uchikura, Tatehiko Wada, Sumito Hoshino, Sonshin Takao, Takashi Aiko, Gregory B. Bulkley, Andrew S. Klein, Zhaoli Sun. Lipopolysaccharides induced increases in Fas-ligand expression by Kupffer cells via mechanisms dependent on reactive oxygen species. Am J Physiol Gastrointest Liver Physiol.  2004 Sep; 287(3):G620-6.
4.Yuichi Nagakawa, Shuji Nomoto, Yukihiko Kato, Robert A. Montgomery, G. Melville Williams, Andrew S.  Klein, Zhaoli Sun. Over-expression of AIF-1 in liver allografts and peripheral blood correlates with acute  rejection after transplantation in rats. Am J Transplantation 2004 Dec; 4(12):1949-57
5.Yuichi Nagakawa, G. Melville Williams, Tsuchida A, Aoki T, Robert A. Montgomery, Andrew S. Klein, Zhaoli Sun. Oxidative mitochandria DNA damage and deletion in hepatocytes of acute rejecting liver allografts: the role of TNF-α. Hepatology 2005, July, 42(1): 208-15.
6.Kosei Maemura, Qizhi Zheng, Tatehiko Wada, Michitaka Ozaki, Sonshin Takao, Gregory B. Bulkley, Andrew S. Klein, Zhaoli Sun. Reactive Oxygen Species are essential mediators for antigen presentation by Kupffer cells. Immunology and Cell Biology 2005 Aug; 83: 336-343.
7.Zhaoli Sun, Xiuying Zhang, Kazhushige Ito, Yulin Li, Robert A Montgomery, Shingo Tachibana, George Melville Williams. Amelioration of Oxidative Mitochondrial DNA Damage and Deletion after Renal Ischemic Injury by the K-ATP Channel Opener Diazoxide. Am J Physiol Renal Physiol. 2008 Mar; 294 (3):F491-8.
8.Locke JE, Sun Z, Warren DS, Sheets TP, Holzer H, Shamblott MJ, Montgomery RA, Cameron AM. Generation of humanized animal livers using embryoid body-derived stem cell transplant. Ann Surg. 2008 Sep; 248(3):487-93.
9.Zhaoli Sun, Xiuying Zhang, Jayme Locke, Qizhi Zheng, Shingo Tachibana, Anna Mae Diehl, G. Melville Williams. Recruitment of Recipient Progenitor Cells in Rat Liver Transplants. Hepatology 2009 Feb; 49(2):587-97.
10.Xiuying Zhang, Shingo Tachibana, Hua Wang, George Melville Williams, Bin Gao, Zhaoli Sun. Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in mice. Hepatology 2010 Accepted

Editorial Activities:
Journal peer review activities: Liver Transplantation (2004-), Free Radical Biology and Medicine (2005-), Hepatology (2007-), Gastroenterology (2008-), Pharmacology Research (2007-), Experimental Cell Research (2006-), BBA - Molecular Basis of Disease (2007-), Human Immunology (2007-), World Journal of Gastroenterology (2008-), Journal of Pharmacological Science (2008-), Archives of Medical Research (2007-), Am J Transplant (2008-), Journal of Clinical Investigation (2009-).

Advisory Committees, Review Groups/Study sections (data, sponsor, role)
NIH Ad hoc Member:
       Study Section of Immune Cell in Hepatic Injury, NIAID Special   
       Emphasis Panel (ZAI1 SV-I (J1)) October/2008;
       NIDDK Special Emphasis Panel (ZRG1 DKUS-K (11)) August/2009.
Member, Advisory Board of Solid Organ Transplantation, Genzyme Corporation, March/2010 

Extramural Funding (current and previous)
Current:
U01 AA018113 (Role: PI)
Date: 07/01/2010 -06/30/2015
Title: Alcoholic Liver Diseases: Damage, Repair and Stem Cell Regeneration
Sponsor: NIAAA/NIH
Total direct cost: $1,452,807
Principal Investigator: Zhaoli Sun

Previous:
R21 AI065488 (Role: PI)
Date: 04/01/06-03/31/09
Title: Repopulation of Liver Allografts by Recipients
Sponsor: NIAID/NIH
Total direct cost: $275,000
Principal investigator: Zhaoli Sun

RO1 DK31764 (Role: PI)
Dates: 7/1/02-6/30/07
Title: Oxidant Signaling in the Enterhepatic Microvasculature
Sponsor: NIDDK/NIH
Total cost: $1,250,000
Principal Investigator: Zhaoli Sun

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