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A case report of hepatic veno-occlusive disease with arthralgia as the first symptom
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摘要:
<正>肝小静脉闭塞症（hepatic veno-occlusive disease,HVOD）指肝小叶中央静脉和肝小叶下静脉狭窄甚至闭塞,继而发生肝细胞萎缩、弥漫性肝纤维化。HVOD的病因多见于野百合碱中毒,近年来造血干细胞移植、化疗、放疗等也成为常见病因。临床可表现为肝脏肿大、疼痛、腹水等。该病临床诊断较为困难,病理检查、影像学检查具有特征性。我科近期明确诊断1例以关节痛为首发表现的HVOD患者,现报告如下。
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[1]McDonald GB, Sharma P, Matthews DE, et al.Veno-occlusivedisease of the liver after bone marrow transplantation:diagnosis, in-cidence, and predisposing factors[J].Hepatology, 1984, 4 (1) :116-122. [2]Jones RJ, Lee KS, Beschorner WE, et al.Veno-occlusive diseaseof the liver following bone marrow transplantation[J].Transplanta-tion, 1987, 44 (6) :778-783. [3]宋宇, 樊艳华.土三七所致肝小静脉闭塞病102例临床分析[J].临床肝胆病杂志, 2011, 27 (5) :496-499. [4]张国华, 孔阿照, 方军伟, 等.肝小静脉闭塞病的CT表现[J].中华放射学杂志, 2006, 40 (3) :250-254. -
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