【Abstract】：Objective To investigate the clinical effect, adaptability, and advantages/disadvantages of primary suture versus T-tube drainage in laparoscopic common bile duct exploration (LCBDE), and to provide reliable evidence for clinical treatment. Methods PubMed, OVID, WOS, EMBASE, Chinese Scientific Journal Full-Text Database, Wanfang Data, and VIP were searched for articles published from January 1, 2005 to December 31, 2016. The articles were screened according to inclusion and exclusion criteria, and RevMan 53 software was used for meta-analysis. Results A total of 12 articles were included, with 1222 patients in total, among whom 616 were given primary suture (observation group) and 606 were given T-tube drainage (control group). There were significant differences between primary suture and T-tube drainage in time of operation (weighted mean difference ［WMD］ =-10.79, 95% confidence interval ［CI］: -13.55 to -8.03, P＜0.001), length of postoperative hospital stay (WMD=-4.16, 95% CI: -4.84 to -3.48, P＜0.001), time to first flatus (WMD=-8.39, 95% CI: -12.50 to -4.27, P＜0.001), biliary drainage time (WMD=-27.06, 95% CI: -51.08 to -3.04, P=0.03), and incidence rate of bile leakage (odds ratio = 0.47, 95% CI: 0.27-0.82, P=0.008). Conclusion Primary suture in LCBDE is safe and effective and has significant advantages over T-tube drainage. Therefore, it holds promise for clinical application.
【Key words】：choledocholithiasis; laparoscopy; primary suture; Meta-analysis