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Application of bacteriophage technique in the treatment of alcoholic liver disease
文章发布日期:2020年10月22日  来源:  作者:马欢,佟静,王炳元  点击次数:113次  下载次数:42次
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【Abstract】:Alcoholic hepatitis (AH) is a severe alcohol-associated liver disease with a mortality rate as high as 40%. A recent study reveals that the exotoxin (cytolysin)-secreting gut bacterium Enterococcus faecalis is a critical factor for AH, which can be eliminated by bacteriophages, and therefore, the use of bacteriophages for the treatment of AH provide a new treatment option for AH. This article introduces this pioneering study and the knowledge of bacteriophages and cytolysin, so as to provide a theoretical basis for the clinical research on AH.
【Key words】:hepatitis,alcoholic; bacteriophages; perforin; therapeutics

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