【Abstract】：Due to its deep anatomic location and complex blood supply characteristics, hepatocellular carcinoma originating from the caudate lobe has become the difficulty in surgical resection, and radiofrequency ablation (RFA) is gradually applied to the treatment of hepatocellular carcinoma originating from the caudate lobe with the help of its advantages of precision and minimal invasiveness. This article briefly describes the anatomic characteristics of the caudate lobe, introduces the advances in radiofrequency approach for the caudate lobe, intraoperative guidance, and selection of RFA needle in detail, and summarizes the surgical safety and effectiveness of RFA associated with the caudate lobe through an analysis of the latest articles in recent ten years. It is concluded that RFA is a promising alternative for the treatment of hepatocellular carcinoma originating from the caudate lobe with the advantages of minimal invasiveness, good repeatability, and few complications, and it can also achieve the goal of complete ablation.
【Key words】：liver neoplasms； radiofrequency ablation； therapeutics