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Research advances in proton pump inhibitor and complications of liver cirrhosis
文章发布日期:2020年10月22日  来源:  作者:刘林祥,聂源,朱萱  点击次数:162次  下载次数:54次
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【Abstract】:Proton pump inhibitor (PPI) is often used for the prevention and treatment of digestive system diseases, and the adverse outcomes caused by the use of PPI are increasingly concerned by scholars. This article elaborates on the association of the complications of liver cirrhosis, such as upper gastrointestinal bleeding, spontaneous bacterial peritonitis, hepatic encephalopathy, hepatocellular carcinoma, and infection, and the change in gut microbiota with the use of PPI, and points out that in clinical practice, it is important to master the medication rules of PPI, understand the risk of complications caused by PPI, and actively improve the complications caused by medication.
【Key words】:liver cirrhosis; proton pump inhibitors; gastrointestinal hemorrhage; peritonitis; hepatic encephalopathy; carcinoma,hepatocellular; gastrointestinal microbiome

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